We have studied the effect of cell boundary on 2D foam, with particular attention to perfect arrays of identical bubbles, and those containing only a single defect with time. We have also examined the effect of the wetness of the foam, observing the stability of two-dimensional foam comprising bubble rafts constrained to a fixed area of liquid surface. Perfectly six-fold coordinated foam appear to be unstable against loss of cohesion, but the lifetime to breakage of the perfect foam increases systematically with changing the cell boundaries. Foams containing a single defect are stable against such breakage due to the elastic stress fields around it.