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Targeting of protein expression in renal disease using siRNA – A review
Published in University of Benin
2020
Volume: 19
   
Issue: 6
Pages: 1313 - 1320
Abstract
The kidneys have rarely been used as a target in the systemic delivery of siRNA when compared to other tissues or organs in the body. This review article deals with various modalities adopted to deliver siRNA to the renal system under different normal and pathophysiological states. In this article, the authors have reviewed extensive clinical data that describe the use of siRNA for the treatment of renal diseases. Conventional and 3D modeling utilizes the existing genome-based RNA libraries, which facilitated the identification of molecular pathways involved in renal diseases. © 2020 The authors. This work is licensed under the Creative Commons TropAttribution J Pharm 4.0 Res, International June 2020; License 19(6): 131
About the journal
JournalTropical Journal of Pharmaceutical Research
PublisherUniversity of Benin
ISSN15965996
Open AccessNo
Authors (3)