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Synthesis, in vitro characterization and antibacterial efficacy of moxifloxacin-loaded chitosan-pullulan-silver-nanocomposite films
A. Shah
Akram Ashour Ashames
Known for
ACPE
BPharm
2021
Last 3 years
Lifetime
Citations
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12
14
Publications
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4
5
M. BuabeidG. Murtaza
Published in Editions de Sante
2020
Volume: 55
   
Abstract
Current study reports the facile synthesis, in-vitro characterization and antibacterial efficacy of novel moxifloxacin (Mox)-loaded chitosan-pullulan-silver-nanocomposite (CSPN) films. Chitosan and pullulan have been notably practiced as stabilizers together with sodium borohydride (NaBH4) utilized as mediator for in-situ silver nanoparticles (AgNPs) synthesis under environment-friendly conditions using aqueous mixture of both polymers. The nanocomposite films served as a promising carrier system for model antibacterial i.e. Mox. The films were prepared via conventional solvent casting of aqueous composite suspension containing Mox. The fabricated nanocomposites were screened for surface plasmon resonance (SPR) peak and nanometric size of AgNPs via UV–Vis spectroscopy and zeta sizer. ...
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CitationCitations - 5
About the journal
JournalJournal of Drug Delivery Science and Technology
PublisherEditions de Sante
Open AccessNo
Concepts (7)
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    Chitosan-silver nanocomposite
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    Elongation at break
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    Moisture content
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    Moxifloxacin
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    Swelling index
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    Tensile strength
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    Water solubility