ArticlesSynthesis, in vitro characterization and antibacterial efficacy of moxifloxacin-loaded chitosan-pullulan-silver-nanocomposite films
Published in Editions de Sante
Current study reports the facile synthesis, in-vitro characterization and antibacterial efficacy of novel moxifloxacin (Mox)-loaded chitosan-pullulan-silver-nanocomposite (CSPN) films. Chitosan and pullulan have been notably practiced as stabilizers together with sodium borohydride (NaBH4) utilized as mediator for in-situ silver nanoparticles (AgNPs) synthesis under environment-friendly conditions using aqueous mixture of both polymers. The nanocomposite films served as a promising carrier system for model antibacterial i.e. Mox. The films were prepared via conventional solvent casting of aqueous composite suspension containing Mox. The fabricated nanocomposites were screened for surface plasmon resonance (SPR) peak and nanometric size of AgNPs via UV–Vis spectroscopy and zeta sizer. ...