Heat and mass transfer in peristalsis of magnetohydrodynamic third-grade material through curved configuration is addressed. Variable characteristics of thermal conductivity and viscosity are taken. Effects of Soret and Dufour are examined. Chemical reaction with activation energy is attended. Compliant properties are subject to channel boundaries. Slip aspects are considered for velocity, temperature and concentration at channel boundaries. Large wavelength and low Reynolds number are invoked. Resulting expressions are computed numerically. The detailed physical interpretations of all the flow quantities are analyzed for various pertinent parameters. Opposite trend of velocity is found for viscosity coefficient and material parameter. Temperature increases for Dufour parameter, whereas concentration decreases for Soret variable. © 2020, Akadémiai Kiadó, Budapest, Hungary.