This case report describes a case of amlodipine induced gingival enlargement in a pre existing periodontitis case. The uniqueness in this case is that the patient exhibited severe enlargement in spite of using the drug at lower dosage within short span of time. The gingival enlargement complicates the periodontal maintenance and aggravates other periodontal diseases. Drug induced enlargements pose a greater problem to dentists as they interfere with oral hygiene practices. So both the dentists and the general practitioner should be aware this adverse reaction to Amlodipine for effective case maintenance.