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Salmonella typhimurium enterotoxin mediated fluid secretion
Khurana S., K. Ganguly N., , Khullar M., N.S. Walia B.
Published in National Library of Medicine
1992
PMID: 1577513
Volume: 95
   
Issue: JAN.
Pages: 17 - 20
Abstract

Unidirectional Na+ and Cl- fluxes were studied in rats treated with S. typhimurium enterotoxin (S-LT). There was net absorption of Na+ and Cl- in the control group, while in the toxin treated animals there was net secretion of Na+ and Cl- (P less than 0.001). There was no change in the transport of D-glucose in the toxin treated group as compared to the control animals. The Na+, K(+)-ATPase pump was unaltered in the S-LT treated animals (198.67 +/- 11.23 nmoles Pi/mg protein/min) as compared to the control group (189.93 +/- 10.09 nmoles Pi/mg protein/min). There was no change in the unidirectional fluxes of Ca+2 in the S-LT treated animals as compared to the control animals, suggesting no change in the permeability of the S-LT treated intestinal membrane to Ca+2.

About the journal
JournalIndian Journal of Medical Research - Section A Infectious Diseases
PublisherNational Library of Medicine
ISSN0019-5340
Open AccessNo