Mobile devices are gaining high popularity due to support for a wide range of applications. However, the mobile devices are resource constrained and many applications require high resources. To cater to this issue, the researchers envision usage of mobile cloud computing technology which offers high performance computing, execution of resource intensive applications, and energy efficiency. This chapter highlights importance of mobile devices, high performance applications, and the computing challenges of mobile devices. It also provides a brief introduction to mobile cloud computing technology, its architecture, types of mobile applications, computation offloading process, effective offloading challenges, and high performance computing application on mobile devises that are enabled by mobile cloud computing technology. © 2016 by IGI Global. All rights reserved.