Introduction: Sessions on rational use of medicines are being conducted at the Manipal College of Medical Sciences, Pokhara, Nepal. Recently, sessions on analyzing rationality of prescriptions have been introduced. The present study was carried out to obtain information on the attitudes of preclinical medical students towards the sessions and note association, if any, of the attitudes with the respondents' characteristics. Methods: Student feedback was collected using an anonymous, self-administered questionnaire. The student attitudes were measured using a modified Likert-type scale. The median total score was calculated and association was determined using appropriate statistical tests. Results: The overall response rate was 73.5% (164 of the 223 students). Indians and Nepalese were the common nationalities and majority of respondents were urban and self-financing. No association was observed of the score with demographic characteristics. Conclusion: The overall student response was positive and the sessions should be continued and strengthened.