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Calcium-Silicate Sodium-Phosphate Fluoride Salt Enhances Enamel Remineralization Following Tooth Bleaching

Hatem El-Damanhoury, , Hanin Kadhim
Published in

Objectives: This study was conducted to evaluate the effect of in-office bleaching on the enamel surface and to assess the efficacy of Calcium Silicate–Sodium Phosphate–Fluoride Salt (Regenerate Enamel; RE) and Novamin Bioactive Glass (Sensodyne; SD) toothpastes in remineralizing bleached enamel.
Methods: Forty Flat enamel surfaces were prepared, finished and polished with up to 1200-grit sandpaper discs. The average baseline surface microhardness was recorded using a micro-indentor (Knoop diamond, 25 g/10 s), baseline surface roughness was measured utilizing atomic force microscopy (AFM), and surface topography/elemental analysis was examined using SEM/EDX. Specimens were randomly divided into two equal groups; No treatment and three applications of 38% Hydrogen Peroxide Bleaching agent (Opalescence R Boost, Ultradent, USA). The samples were further divided into four subgroups (n=10) according to the remineralization protocol; negative control (kept in artificial saliva for 24 hours), SD toothpaste, RE toothpaste, or RE followed by application of NR-5 boosting Serum (RE+NR). Each remineralizing material was applied for 5 min two times a day for 7 days. The three aforementioned assessments were repeated after each bleaching session then re-repeated following each remineralization protocol. Data were statistically analyzed using two-way analysis of variance (ANOVA) and Bonferroni Post Hoc multiple comparison tests (α=0.05).
Results: Bleaching of enamel caused a significant reduction in Hardness and produced a rough surface that simulates acid erosion. Both remineralization materials were able to significantly reduce the surface roughness and increase the hardness after bleaching (p<0.05), except when the NR-5 serum was used. RE exhibited higher remineralization capacity in comparison to SD.
Conclusions: The remineralization efficacy of RE is higher than that of SD when used to reverse the effect of in-office bleaching on the enamel surface.

About the journal
JournalInternational Association of Dental Research
Open AccessYes