COVID-19, which is instigated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused the pandemic. This disease provoked with its epicenter in China. Belonging to the Coronaviridae family of viruses, it is a new strain of β type of coronavirus. The World Health Organization (WHO) declared its name as ‘SARS-CoV-2’. In January 2020, the WHO declared COVID-19 as the sixth public-health emergency of international suffering. Lack of etymology, precautionary measures, specified drug or vaccination for this viral infection was the main reason for the epidemic. Hence, there was an extensive need for the scientists throughout the globe to work on it. Some potential inhibitors have been reported to possibly treat COVID-19 affected patients. Likewise, a new technique, which is the Plasma Therapy, is used in the treatment. In this context, this review aims to summarize the epidemiology, virology, mode of dissemination, diagnosis, treatment, and prevention measures of COVID-19. © Engineered Science Publisher LLC 2020.