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Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis

  • University of Cape Town
  • University of Namibia
  • University of the Western Cape
  • Morogoro Regional Referral Hospital
  • National Health Laboratory Services

Research output: Contribution to journalReview articlepeer-review

125 Scopus citations

Abstract

A healthy vaginal microbiota is considered to be significant for maintaining vaginal health and preventing infections. However, certain vaginal bacterial commensal species serve an important first line of defense of the body. Any disruption of this microbial barrier might result in a number of urogenital conditions including aerobic vaginitis (AV) and bacterial vaginosis (BV). The health of the vagina is closely associated with inhabitant microbiota. Furthermore, these microbes maintain a low vaginal pH, prevent the acquisition of pathogens, stimulate or moderate the local innate immune system, and further protect against complications during pregnancies. Therefore, this review will focus on vaginal microbial “health” in the lower reproductive tract of women and on the physiological characteristics that determine the well-being of reproductive health. In addition, we explore the distinct versus shared characteristics of BV and AV, which are commonly associated with increased risk for preterm delivery.

Original languageEnglish
Article number78
JournalFrontiers in Public Health
Volume6
DOIs
StatePublished - 26 Mar 2018
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • aerobic vaginitis
  • bacterial vaginosis
  • group B Streptococcus
  • preterm birth
  • vaginal microbiomes

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