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Uncertainty-based Gompertz growth model for tumor population and its numerical analysis

  • B.S. Abdur Rahman Crescent Institute of Science and Technology
  • International College of Engineering
  • International Center for Basic and Applied Sciences
  • Balikesir University

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

For treating cancer, tumor growth models have shown to be a valuable resource, whether they are used to develop therapeutic methods paired with process control or to simulate and evaluate treatment processes. In addition, a fuzzy mathematical model is a tool for monitoring the influences of various elements and creating behavioral assessments. It has been designed to decrease the ambiguity of model parameters to obtain a reliable mathematical tumor development model by employing fuzzy logic.The tumor Gompertz equation is shown in an imprecise environment in this study. It considers the whole cancer cell population to be vague at any given time, with the possibility distribution function determined by the initial tumor cell population, tumor net population rate, and carrying capacity of the tumor. Moreover, this work provides information on the expected tumor cell population in the maximum period. This study examines fuzzy tumor growth modeling insights based on fuzziness to reduce tumor uncertainty and achieve a degree of realism. Finally, numerical simulations are utilized to show the significant conclusions of the proposed study.

Original languageEnglish
Pages (from-to)137-150
Number of pages14
JournalInternational Journal of Optimization and Control: Theories and Applications
Volume12
Issue number2
DOIs
StatePublished - 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Fuzzy sets
  • Gompertz model
  • Possibility distribution function
  • Tumor growth modeling

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