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The stationary distribution and extinction of a double thresholds HTLV-I infection model with nonlinear CTL immune response disturbed by white noise

  • China University of Petroleum (East China)
  • King Abdulaziz University
  • Quaid-I-Azam University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

This paper investigates the stochastic HTLV-I infection model with CTL immune response, and the corresponding deterministic model has two basic reproduction numbers. We consider the nonlinear CTL immune response for the interaction between the virus and the CTL immune cells. Firstly, for the theoretical needs of system dynamical behavior, we prove that the stochastic model solution is positive and global. In addition, we obtain the existence of ergodic stationary distribution by stochastic Lyapunov functions. Meanwhile, sufficient condition for the extinction of the stochastic system is acquired. Reasonably, the dynamical behavior of deterministic model is included in our result of stochastic model when the white noise disappears.

Original languageEnglish
Article number1950058
JournalInternational Journal of Biomathematics
Volume12
Issue number5
DOIs
StatePublished - 1 Jul 2019
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • CD4 + T cells
  • CTL immune response
  • HTLV-I infection
  • extinction
  • stationary distribution

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