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The role of diverse nanoparticles in oxidative stress: In vitro and in vivo studies

  • Shanmugam Rajeshkumar
  • , Durairaj Sekar
  • , Devaraj Ezhilarasan
  • , Thangavelu Lakshmi
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Nanoparticles are a very advanced area of nanotechnology and play an important role in medical sciences and technology. Nanoparticles such as polymer and metal nanoparticles are widely used in applications for antioxidant activity. Nonenzymatic antioxidant assays using free radical-scavenging activity of nanoparticles have been investigated using different methods such as 2, 2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assays, nitric oxide radical inhibition assays, superoxide anion-scavenging activity, reducing power, determination of total phenolic compounds and hydroxyl radical-scavenging assays. The investigated metal nanoparticle included gold, zinc oxide, copper, silver, zirconium oxide and selenium, and the polymer nanoparticles include chitosan and silica.

Original languageEnglish
Title of host publicationRole of Oxidative Stress in Pathophysiology of Diseases
PublisherSpringer Singapore
Pages27-48
Number of pages22
ISBN (Electronic)9789811515682
ISBN (Print)9789811515675
DOIs
StatePublished - 1 Jan 2020
Externally publishedYes

Keywords

  • Antioxidant activity
  • Characterization
  • Metal nanoparticles
  • Polymers
  • Synthesis

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