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Synbioticsin Gastric Cancer

  • Nitin Verma
  • , Komal Thapa
  • , Gagandeep Kaur
  • , Kamal Dua
  • Chitkara University
  • University of Technology Sydney

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The growth of human gut microbiota is critical for, the metabolism and synthesis of short-chain fatty acids, nutrition absorption and vitamins, resistance to pathogenic microorganisms, and the regulation of a healthy immune system. Various diseases like inflammatory bowel disease, malignancies, obesity, asthma, or mental problems are related to a microbiota imbalance. Synbiotics are a combination of probiotics (good bacteria for your gut) and prebiotics (non-digestible fibers that help to grow these bacteria). They are specifically mixtures of these two products that work synergistically in the digestive tract. Synbiotics work by allowing prebiotics to assist probiotics to grow in your intestines. This may assist to balance the gut bacteria, which is beneficial to your gut health, immune system, and metabolism. Many commercial probiotic products are now accepted to be relatively safe and could be utilized as a supplement for tumor prevention and treatment. Synbiotics have also been found to reduce post-operative inflammation in a number of cancer patients. In this book chapter, the underlying mechanism of gastric cancer or therapeutic effects of synbiotics in gastric cancer have been updated. However, additional clinical trials are required to prove synbiotics as a viable alternative cancer treatment.

Original languageEnglish
Title of host publicationSynbiotics for the Management of Cancer
PublisherSpringer Nature
Pages157-173
Number of pages17
ISBN (Electronic)9789811975509
ISBN (Print)9789811975493
DOIs
StatePublished - 1 Jan 2023
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Gastric cancer
  • Gut microbiota
  • Prebiotics
  • Probiotic
  • Synbiotics

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