TY - CHAP
T1 - Surface Functionalization of 2D MOs for Enhanced Biocompatibility and Biomedical Applications
AU - Abdelmonem, Mohamed
AU - Albert, Emmellie Laura
AU - Norman, Ashreen
AU - Tarmizie, Emma Ziezie
AU - Zyoud, Samer H.
AU - Abdullah, Che Azurahanim Che
N1 - Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2024.
PY - 2024
Y1 - 2024
N2 - Metal oxides (MOs) like titanium dioxide (TiO2), zinc oxide (ZnO), and iron oxide (Fe2O3) possess unique characteristics such as high surface area, biocompatibility, and biodegradability that render them valuable in biomedicine. However, their innate toxicity limits their usage in biomedical applications. Surface functionalization techniques such as coating, grafting, and doping can modify the surface of 2D MOs, thereby enhancing their biocompatibility, reducing their toxicity, and improving their selectivity towards biological entities. Moreover, surface functionalization can boost the stability and durability of these nanomaterials, thereby making them suitable for prolonged biomedical applications. This paper presents a review of the current state of surface functionalization techniques for 2D MOs and their potential applications in drug delivery, imaging, and biosensors. The findings of this chapter will give a future prospective related to the usage of 2D MOs in biomedical application, especially in vivo in a more efficient and targeted manner, providing opportunities to advance biomedical applications.
AB - Metal oxides (MOs) like titanium dioxide (TiO2), zinc oxide (ZnO), and iron oxide (Fe2O3) possess unique characteristics such as high surface area, biocompatibility, and biodegradability that render them valuable in biomedicine. However, their innate toxicity limits their usage in biomedical applications. Surface functionalization techniques such as coating, grafting, and doping can modify the surface of 2D MOs, thereby enhancing their biocompatibility, reducing their toxicity, and improving their selectivity towards biological entities. Moreover, surface functionalization can boost the stability and durability of these nanomaterials, thereby making them suitable for prolonged biomedical applications. This paper presents a review of the current state of surface functionalization techniques for 2D MOs and their potential applications in drug delivery, imaging, and biosensors. The findings of this chapter will give a future prospective related to the usage of 2D MOs in biomedical application, especially in vivo in a more efficient and targeted manner, providing opportunities to advance biomedical applications.
KW - Biocompatibility
KW - Biodegradability
KW - Biomedicine
KW - High surface area
KW - Metal oxides (MO)
UR - https://www.scopus.com/pages/publications/105033172389
U2 - 10.1007/978-3-031-57843-4_7
DO - 10.1007/978-3-031-57843-4_7
M3 - Chapter
AN - SCOPUS:105033172389
T3 - Lecture Notes in Nanoscale Science and Technology
SP - 175
EP - 198
BT - Lecture Notes in Nanoscale Science and Technology
PB - Springer Nature
ER -