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Stationary distribution of an HIV model with general nonlinear incidence rate and stochastic perturbations

  • China University of Petroleum (East China)
  • Faculty of Sciences, King Abdulaziz University
  • Quaid-I-Azam University

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

We present a stochastic HIV infection model with logistic target cell growth, general nonlinear incidence rate, CTL immune response and parameter perturbations. Through a rigorous analysis of the model, we obtain that the solution of the model is positive and global. A critical condition R0 s of the model is derived, which depends not only on the general incidence function but also on the noise intensities. Under certain assumptions, by constructing suitable Lyapunov functions, we find that the system has a unique ergodic stationary distribution when R0 s>1. We further explore the effect of the noise intensity on model behavior. Our conclusion improves and generalizes the results of the existing HIV stochastic models.

Original languageEnglish
Pages (from-to)6610-6637
Number of pages28
JournalJournal of the Franklin Institute
Volume356
Issue number12
DOIs
StatePublished - Aug 2019
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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