Smart polymers in drug delivery

Sushant Lakkadwala; Sanko Nguyen; Jerry Nesamony; Ajit S. Narang; Sai Hs Boddu

doi:10.1007/978-3-319-20206-8_7

Smart polymers in drug delivery

Sushant Lakkadwala
, Sanko Nguyen
, Jerry Nesamony
, Ajit S. Narang
, Sai Hs Boddu

Bristol-Myers Squibb
University of Toledo

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

7 Scopus citations

Abstract

Smart polymers or stimuli-responsive polymers typically change their physical properties and/or structure in response to relatively minor changes in the stimulus. Changes in the environment that affect polymer properties can be called as the stimuli, while the resulting changes in the polymer and the system (such as dissolved state of the polymer in a solvent) has been termed as the response. The changes in the environment that have been exploited for biopharmaceutical applications are exemplified by pH, ionic strength, temperature, light, and magnetic or electric field. This chapter will highlight most popular smart polymers used in drug delivery.

Original language	English
Title of host publication	Excipient Applications in Formulation Design and Drug Delivery
Publisher	Springer International Publishing
Pages	169-199
Number of pages	31
ISBN (Electronic)	9783319202068
ISBN (Print)	9783319202051
DOIs	https://doi.org/10.1007/978-3-319-20206-8_7
State	Published - 1 Jan 2015
Externally published	Yes

Keywords

Antigen-sensitive polymers
Dual stimuli-sensitive polymers
Electrosensitive polymers
Enzyme-sensitive polymers
Light-sensitive polymers
Magnetically-sensitive polymers
PH-sensitive polymers
Phase-sensitive polymers
Temperature-sensitive polymers
Ultrasoundsensitive polymers

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10.1007/978-3-319-20206-8_7

Cite this

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AU - Lakkadwala, Sushant

AU - Nguyen, Sanko

AU - Nesamony, Jerry

AU - Narang, Ajit S.

AU - Boddu, Sai Hs

N1 - Publisher Copyright: © Springer International Publishing Switzerland 2015.

PY - 2015/1/1

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N2 - Smart polymers or stimuli-responsive polymers typically change their physical properties and/or structure in response to relatively minor changes in the stimulus. Changes in the environment that affect polymer properties can be called as the stimuli, while the resulting changes in the polymer and the system (such as dissolved state of the polymer in a solvent) has been termed as the response. The changes in the environment that have been exploited for biopharmaceutical applications are exemplified by pH, ionic strength, temperature, light, and magnetic or electric field. This chapter will highlight most popular smart polymers used in drug delivery.

AB - Smart polymers or stimuli-responsive polymers typically change their physical properties and/or structure in response to relatively minor changes in the stimulus. Changes in the environment that affect polymer properties can be called as the stimuli, while the resulting changes in the polymer and the system (such as dissolved state of the polymer in a solvent) has been termed as the response. The changes in the environment that have been exploited for biopharmaceutical applications are exemplified by pH, ionic strength, temperature, light, and magnetic or electric field. This chapter will highlight most popular smart polymers used in drug delivery.

KW - Antigen-sensitive polymers

KW - Dual stimuli-sensitive polymers

KW - Electrosensitive polymers

KW - Enzyme-sensitive polymers

KW - Light-sensitive polymers

KW - Magnetically-sensitive polymers

KW - PH-sensitive polymers

KW - Phase-sensitive polymers

KW - Temperature-sensitive polymers

KW - Ultrasoundsensitive polymers

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DO - 10.1007/978-3-319-20206-8_7

M3 - Chapter

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SN - 9783319202051

SP - 169

EP - 199

BT - Excipient Applications in Formulation Design and Drug Delivery

PB - Springer International Publishing

ER -

Smart polymers in drug delivery

Abstract

Keywords

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