Role of coenzyme q10 in periodontal therapy: A therapeutic review

Periodontal disease (Gum disease) is a highly prevalent disease that is associated with swollen gums, bleeding, pain, redness of the gums and mobility of teeth. It's a multifactorial disease in which bacteria, host and environment play a significant role in causing this disease and progression of the disease. Interaction between the host and bacteria lead to wide spread inflammatory reaction and formation of reactive oxygen species. Clinical studies show that people with periodontal disease tend to have low levels of antioxidants like CoQ10 in their gingiva. Coenzyme Q10 (CoQ10) is a compound found naturally in the human body. Because of its ubiquitous presence in nature and its quinone structure (similar to that of vitamin K), CoQ10 is also known as ubiquinone. CoQ10 is used in the management of Heart disease, heart failure, high blood pressure, high cholesterol, Diabetes, Breast cancer, AIDS, Angina pectoris, Gastric ulcer, Migraine and Allergies. Hence this review article discusses the potential use of Co enzyme Q 10 in the treatment of several disease conditions and focuses a bird's view on the management of periodontal disease.