Recent trends of nano-material as antimicrobial agents

Taru Aggarwal; Ridhima Wadhwa; Noopur Thapliyal; Riya Gupta; Philip Michael Hansbro; Kamal Dua; Pawan Kumar Maurya

doi:10.1007/978-981-13-6004-6_5

Recent trends of nano-material as antimicrobial agents

Taru Aggarwal
, Ridhima Wadhwa
, Noopur Thapliyal
, Riya Gupta
, Philip Michael Hansbro
, Kamal Dua
, Pawan Kumar Maurya

ICAR - Indian Agricultural Research Institute
South Asian University
Amity University, Noida
Hunter Medical Research Institute, Australia
Centenary Institute
University of Technology Sydney
Central University of Haryana

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

7 Scopus citations

Abstract

Nanomaterial has been employed as an alternative to antibiotics, diagnostic tools and delivery of therapeutics. In particular, nanomaterial has grabbed the attention of researchers due to their antimicrobial properties due to the emergence of multi-drug resistance of several micro-organisms. The present chapter highlights the antimicrobial nanomaterials with their mechanism of action along with their broad spectrum applications such as silver nanomaterial is antimicrobial in nature and is effective in drug delivery. Metallic, non-metallic and natural/ biodegradable nanomaterials have been discussed as potential antimicrobial and their mode of action. The mechanism of antimicrobial nanomaterial is poorly understood, but oxidative stress, non-oxidative action, inhibition of cell adhesion, decline in biofilm formation, obstructed quoram sensing and metal ion release are attributed to be as the major reasons. In addition, the limitation and toxicity with the clinical and environmental applications are also described.

Original language	English
Title of host publication	Nanotechnology in Modern Animal Biotechnology
Subtitle of host publication	Recent Trends and Future Perspectives
Publisher	Springer Singapore
Pages	173-193
Number of pages	21
ISBN (Electronic)	9789811360046
ISBN (Print)	9789811360039
DOIs	https://doi.org/10.1007/978-981-13-6004-6_5
State	Published - 30 Mar 2019
Externally published	Yes

Keywords

Antimicrobial
Biofilm
Drug resistance
Nanomaterial
Oxidative stress
Toxicity

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10.1007/978-981-13-6004-6_5

Cite this

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abstract = "Nanomaterial has been employed as an alternative to antibiotics, diagnostic tools and delivery of therapeutics. In particular, nanomaterial has grabbed the attention of researchers due to their antimicrobial properties due to the emergence of multi-drug resistance of several micro-organisms. The present chapter highlights the antimicrobial nanomaterials with their mechanism of action along with their broad spectrum applications such as silver nanomaterial is antimicrobial in nature and is effective in drug delivery. Metallic, non-metallic and natural/ biodegradable nanomaterials have been discussed as potential antimicrobial and their mode of action. The mechanism of antimicrobial nanomaterial is poorly understood, but oxidative stress, non-oxidative action, inhibition of cell adhesion, decline in biofilm formation, obstructed quoram sensing and metal ion release are attributed to be as the major reasons. In addition, the limitation and toxicity with the clinical and environmental applications are also described.",

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AU - Thapliyal, Noopur

AU - Gupta, Riya

AU - Hansbro, Philip Michael

AU - Dua, Kamal

AU - Maurya, Pawan Kumar

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N2 - Nanomaterial has been employed as an alternative to antibiotics, diagnostic tools and delivery of therapeutics. In particular, nanomaterial has grabbed the attention of researchers due to their antimicrobial properties due to the emergence of multi-drug resistance of several micro-organisms. The present chapter highlights the antimicrobial nanomaterials with their mechanism of action along with their broad spectrum applications such as silver nanomaterial is antimicrobial in nature and is effective in drug delivery. Metallic, non-metallic and natural/ biodegradable nanomaterials have been discussed as potential antimicrobial and their mode of action. The mechanism of antimicrobial nanomaterial is poorly understood, but oxidative stress, non-oxidative action, inhibition of cell adhesion, decline in biofilm formation, obstructed quoram sensing and metal ion release are attributed to be as the major reasons. In addition, the limitation and toxicity with the clinical and environmental applications are also described.

AB - Nanomaterial has been employed as an alternative to antibiotics, diagnostic tools and delivery of therapeutics. In particular, nanomaterial has grabbed the attention of researchers due to their antimicrobial properties due to the emergence of multi-drug resistance of several micro-organisms. The present chapter highlights the antimicrobial nanomaterials with their mechanism of action along with their broad spectrum applications such as silver nanomaterial is antimicrobial in nature and is effective in drug delivery. Metallic, non-metallic and natural/ biodegradable nanomaterials have been discussed as potential antimicrobial and their mode of action. The mechanism of antimicrobial nanomaterial is poorly understood, but oxidative stress, non-oxidative action, inhibition of cell adhesion, decline in biofilm formation, obstructed quoram sensing and metal ion release are attributed to be as the major reasons. In addition, the limitation and toxicity with the clinical and environmental applications are also described.

KW - Antimicrobial

KW - Biofilm

KW - Drug resistance

KW - Nanomaterial

KW - Oxidative stress

KW - Toxicity

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BT - Nanotechnology in Modern Animal Biotechnology

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Recent trends of nano-material as antimicrobial agents

Abstract

Keywords

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