Recent advances in chronotherapy targeting respiratory diseases

Keshav Raj Paudel; Saurav Kumar Jha; Venkata Sita Rama Raju Allam; Parteek Prasher; Piyush Kumar Gupta; Rahul Bhattacharjee; Niraj Kumar Jha; Sukriti Vishwas; Sachin K. Singh; Jesus Shrestha; Mohammad Imran; Nisha Panth; Dinesh Kumar Chellappan; Majid Ebrahimi Warkiani; Philip M. Hansbro; Kamal Dua

doi:10.3390/pharmaceutics13122008

Recent advances in chronotherapy targeting respiratory diseases

Keshav Raj Paudel
, Saurav Kumar Jha
, Venkata Sita Rama Raju Allam
, Parteek Prasher
, Piyush Kumar Gupta
, Rahul Bhattacharjee
, Niraj Kumar Jha
, Sukriti Vishwas
, Sachin K. Singh
, Jesus Shrestha
, Mohammad Imran
, Nisha Panth
, Dinesh Kumar Chellappan
, Majid Ebrahimi Warkiani
, Philip M. Hansbro
, Kamal Dua

Centenary Institute
University of Technology Sydney
Mokpo National University
Uppsala University
University of Petroleum and Energy Studies
Sharda University
Kalinga Institute of Industrial Technology
Lovely Professional University
Jamia Hamdard University
International Medical University

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep–wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual’s circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.

Original language	English
Article number	2008
Journal	Pharmaceutics
Volume	13
Issue number	12
DOIs	https://doi.org/10.3390/pharmaceutics13122008
State	Published - Dec 2021
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Asthma
Chronic obstructive pulmonary disease
Chronotherapy
Circadian rhythm
Lung cancer
Pulmonary fibrosis

Access to Document

10.3390/pharmaceutics13122008

Cite this

Paudel, K. R., Jha, S. K., Allam, V. S. R. R., Prasher, P., Gupta, P. K., Bhattacharjee, R., Jha, N. K., Vishwas, S., Singh, S. K., Shrestha, J., Imran, M., Panth, N., Chellappan, D. K., Warkiani, M. E., Hansbro, P. M., & Dua, K. (2021). Recent advances in chronotherapy targeting respiratory diseases. Pharmaceutics, 13(12), Article 2008. https://doi.org/10.3390/pharmaceutics13122008

@article{48f46711246f4097bb822f5ff90a1a4a,

title = "Recent advances in chronotherapy targeting respiratory diseases",

abstract = "Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep–wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual{\textquoteright}s circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.",

keywords = "Asthma, Chronic obstructive pulmonary disease, Chronotherapy, Circadian rhythm, Lung cancer, Pulmonary fibrosis",

author = "Paudel, \{Keshav Raj\} and Jha, \{Saurav Kumar\} and Allam, \{Venkata Sita Rama Raju\} and Parteek Prasher and Gupta, \{Piyush Kumar\} and Rahul Bhattacharjee and Jha, \{Niraj Kumar\} and Sukriti Vishwas and Singh, \{Sachin K.\} and Jesus Shrestha and Mohammad Imran and Nisha Panth and Chellappan, \{Dinesh Kumar\} and Warkiani, \{Majid Ebrahimi\} and Hansbro, \{Philip M.\} and Kamal Dua",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = dec,

doi = "10.3390/pharmaceutics13122008",

language = "English",

volume = "13",

journal = "Pharmaceutics",

issn = "1999-4923",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "12",

}

TY - JOUR

T1 - Recent advances in chronotherapy targeting respiratory diseases

AU - Paudel, Keshav Raj

AU - Jha, Saurav Kumar

AU - Allam, Venkata Sita Rama Raju

AU - Prasher, Parteek

AU - Gupta, Piyush Kumar

AU - Bhattacharjee, Rahul

AU - Jha, Niraj Kumar

AU - Vishwas, Sukriti

AU - Singh, Sachin K.

AU - Shrestha, Jesus

AU - Imran, Mohammad

AU - Panth, Nisha

AU - Chellappan, Dinesh Kumar

AU - Warkiani, Majid Ebrahimi

AU - Hansbro, Philip M.

AU - Dua, Kamal

PY - 2021/12

Y1 - 2021/12

N2 - Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep–wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual’s circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.

AB - Respiratory diseases contribute to a significant percentage of mortality and morbidity worldwide. The circadian rhythm is a natural biological process where our bodily functions align with the 24 h oscillation (sleep–wake cycle) process and are controlled by the circadian clock protein/gene. Disruption of the circadian rhythm could alter normal lung function. Chronotherapy is a type of therapy provided at specific time intervals based on an individual’s circadian rhythm. This would allow the drug to show optimum action, and thereby modulate its pharmacokinetics to lessen unwanted or unintended effects. In this review, we deliberated on the recent advances employed in chrono-targeted therapeutics for chronic respiratory diseases.

KW - Asthma

KW - Chronic obstructive pulmonary disease

KW - Chronotherapy

KW - Circadian rhythm

KW - Lung cancer

KW - Pulmonary fibrosis

UR - https://www.scopus.com/pages/publications/85120791280

U2 - 10.3390/pharmaceutics13122008

DO - 10.3390/pharmaceutics13122008

M3 - Review article

AN - SCOPUS:85120791280

SN - 1999-4923

VL - 13

JO - Pharmaceutics

JF - Pharmaceutics

IS - 12

M1 - 2008

ER -

Recent advances in chronotherapy targeting respiratory diseases

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this