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Promises of Molecular Pharmaceutics in the Development of Novel Drug Delivery Formulations

  • Parveen Kumar
  • , Benu Chaudhary
  • , Vivek Jain
  • , Sanjula Baboota
  • , Palanisamy Shivanandy
  • , Khalid Saad Alharbi
  • , Mohammed M. Ghoneim
  • , Sultan Alshehri
  • , Syed Sarim Imam
  • , Gaurav Gupta
  • , Madan Mohan Gupta
  • Shri Ram College of Pharmacy
  • Guru Gobind Singh College of Pharmacy
  • CT University
  • Mohan Lal Sukhadia University
  • Jamia Hamdard University
  • International Medical University
  • Al Jouf University
  • Almaarefa University
  • King Saud University
  • Suresh Gyan Vihar University
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)
  • Faculty of Medical Sciences

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Molecular pharmaceutics play a critical role in the drug delivery system, representing the direct interconnection of drug bioavailability with its molecular form. There is a diversity in the molecular structures by which it affects its properties, such as amorphous form, crystalline form, partial-amorphous molecular dispersion, and disordered state. The active pharmaceutical ingredient (API) and the excipients utilized in the formulation process contain various divergent modes used in the formulation process. They include better formulations of any type to obtain good quality pharmaceutical prod-ucts. This review reveals how the molecular states affect the API and are important in maintaining the quality of dosage forms. Furthermore, the physio-chemical properties of the components and various pharmaceutical approaches employed in the formulation of dosage forms are studied from the point of view of molecular pharmaceutics.

Original languageEnglish
Pages (from-to)1262-1274
Number of pages13
JournalCurrent Drug Delivery
Volume20
Issue number9
DOIs
StatePublished - 2023
Externally publishedYes

Keywords

  • Molecular pharmaceutics
  • active pharmaceutical ingredients
  • drug delivery
  • formulation
  • microparticles
  • polymer

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