Poly(vinylpyrrolidone)

Rajendra Awasthi; Satish Manchanda; Poppy Das; Vinodhini Velu; Himaja Malipeddi; Kavita Pabreja; Terezinha D.J.A. Pinto; Gaurav Gupta; Kamal Dua

doi:10.1016/B978-0-08-101750-0.00009-X

Poly(vinylpyrrolidone)

Rajendra Awasthi
, Satish Manchanda
, Poppy Das
, Vinodhini Velu
, Himaja Malipeddi
, Kavita Pabreja
, Terezinha D.J.A. Pinto
, Gaurav Gupta
, Kamal Dua

NKBR College of Pharmacy and Research Center
Delhi Institute of Pharmaceutical Sciences and Research
Vellore Institute of Technology
University of Newcastle
Universidade de São Paulo
Jaipur National University
University of Technology Sydney
Shoolini University of Biotechnology and Management Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

49 Scopus citations

Abstract

Poly(vinylpyrrolidone) (PVP) is one of the most commonly employed synthetic hydrophilic (nonionic) excipient in pharmaceutical formulations. Professor Walter Rappe and his team first developed this excipient during the 1930s and it is now gaining popularity due to its properties such as being nonantigenic, and hence avoiding the danger of infectious diseases inherent in blood. This chapter covers the basic introduction, physicochemical properties, synthesis, and the applications of PVP for its applications in pharmaceutical preparations such as solid, liquid, and semi-solid dosage forms including the PVP-based patented pharmaceutical products.

Original language	English
Title of host publication	Engineering of Biomaterials for Drug Delivery Systems
Subtitle of host publication	Beyond Polyethylene Glycol
Publisher	Elsevier Inc.
Pages	255-272
Number of pages	18
ISBN (Electronic)	9780081017517
ISBN (Print)	9780081017500
DOIs	https://doi.org/10.1016/B978-0-08-101750-0.00009-X
State	Published - 27 Jan 2018
Externally published	Yes

Keywords

Crospovidone
Pharmaceutical excipient
Poly(vinylpyrrolidone)
Povidone

Access to Document

10.1016/B978-0-08-101750-0.00009-X

Cite this

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title = "Poly(vinylpyrrolidone)",

abstract = "Poly(vinylpyrrolidone) (PVP) is one of the most commonly employed synthetic hydrophilic (nonionic) excipient in pharmaceutical formulations. Professor Walter Rappe and his team first developed this excipient during the 1930s and it is now gaining popularity due to its properties such as being nonantigenic, and hence avoiding the danger of infectious diseases inherent in blood. This chapter covers the basic introduction, physicochemical properties, synthesis, and the applications of PVP for its applications in pharmaceutical preparations such as solid, liquid, and semi-solid dosage forms including the PVP-based patented pharmaceutical products.",

keywords = "Crospovidone, Pharmaceutical excipient, Poly(vinylpyrrolidone), Povidone",

author = "Rajendra Awasthi and Satish Manchanda and Poppy Das and Vinodhini Velu and Himaja Malipeddi and Kavita Pabreja and Pinto, \{Terezinha D.J.A.\} and Gaurav Gupta and Kamal Dua",

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doi = "10.1016/B978-0-08-101750-0.00009-X",

language = "English",

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T1 - Poly(vinylpyrrolidone)

AU - Awasthi, Rajendra

AU - Manchanda, Satish

AU - Das, Poppy

AU - Velu, Vinodhini

AU - Malipeddi, Himaja

AU - Pabreja, Kavita

AU - Pinto, Terezinha D.J.A.

AU - Gupta, Gaurav

AU - Dua, Kamal

PY - 2018/1/27

Y1 - 2018/1/27

N2 - Poly(vinylpyrrolidone) (PVP) is one of the most commonly employed synthetic hydrophilic (nonionic) excipient in pharmaceutical formulations. Professor Walter Rappe and his team first developed this excipient during the 1930s and it is now gaining popularity due to its properties such as being nonantigenic, and hence avoiding the danger of infectious diseases inherent in blood. This chapter covers the basic introduction, physicochemical properties, synthesis, and the applications of PVP for its applications in pharmaceutical preparations such as solid, liquid, and semi-solid dosage forms including the PVP-based patented pharmaceutical products.

AB - Poly(vinylpyrrolidone) (PVP) is one of the most commonly employed synthetic hydrophilic (nonionic) excipient in pharmaceutical formulations. Professor Walter Rappe and his team first developed this excipient during the 1930s and it is now gaining popularity due to its properties such as being nonantigenic, and hence avoiding the danger of infectious diseases inherent in blood. This chapter covers the basic introduction, physicochemical properties, synthesis, and the applications of PVP for its applications in pharmaceutical preparations such as solid, liquid, and semi-solid dosage forms including the PVP-based patented pharmaceutical products.

KW - Crospovidone

KW - Pharmaceutical excipient

KW - Poly(vinylpyrrolidone)

KW - Povidone

UR - https://www.scopus.com/pages/publications/85046851708

U2 - 10.1016/B978-0-08-101750-0.00009-X

DO - 10.1016/B978-0-08-101750-0.00009-X

M3 - Chapter

AN - SCOPUS:85046851708

SN - 9780081017500

SP - 255

EP - 272

BT - Engineering of Biomaterials for Drug Delivery Systems

PB - Elsevier Inc.

ER -

Poly(vinylpyrrolidone)

Abstract

Keywords

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