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Plant-based synthesis, characterization approaches, applications and toxicity of silver nanoparticles: A comprehensive review

  • Shijith Thomas
  • , Richard A. Gonsalves
  • , Jomy Jose
  • , Samer H. Zyoud
  • , Anupama R. Prasad
  • , Julia Garvasis
  • Vimal Jyothi Engineering College, Kannur
  • St. Aloysius College
  • Christ College (Autonomous)
  • University of Calicut

Research output: Contribution to journalReview articlepeer-review

68 Scopus citations

Abstract

The development of an environmentally benign method for the synthesis of nanoparticles has been facilitated by green chemistry. “Green synthesis” uses a range of biological elements like microbes, plants, and other biodegradable materials to produce NPs. Active biomolecules that are secreted by natural strains and present in the plant extracts serve as both reducing and capping/stabilizing agents. Microorganisms' intracellular enzymes can reduce metal ions, which explains how NPs might potentially nucleate. Plant-based synthesis of nanomaterials is particularly promising owing to abundant resources, simplicity of synthesis, and low cost. Silver nanoparticles (AgNPs) are attracting great attention in the research community due to their wide variety of applications in chemistry, food technology, microbiology, and biomedicine. Recent years have seen a large amount of research on the bio-genic synthesis of AgNPs employing biomaterials like plant extract and bacteria as reducing agents. Herein we discuss a thorough overview of the plant-based synthesis of silver nanoparticles (AgNPs), characterization approaches, applications, and toxicity. The review covers the green chemistry and nanotechnology elements of producing AgNPs, including a thorough discussion of the plant extract mediated synthesis, detailed formation mechanism, and a well-balanced emphasis on hazards and advantages. Based on current developments, the optimisation strategies, applications, and interdisciplinary characteristics are also covered in detail.

Original languageEnglish
Pages (from-to)135-149
Number of pages15
JournalJournal of Biotechnology
Volume394
DOIs
StatePublished - 10 Nov 2024

Keywords

  • AgNPs
  • Applications
  • Characterization
  • Plant extract
  • Toxicity

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