Phytochemical, pharmacological, and pharmacognostic overview of Merremia tridentata (L.) Hallier

Merremia tridentate Linn., also known Prasarini in ayurveda and siddha text, is a species of plant in the family Convolvulaceae. The plant is a native to India, and is found in the Upper Gangetic Plain, Bihar, Orissa, West Bengal, South India, and Gujarat. This plant is used extensively in ayurveda as a laxative, astringent, and anti-inflammatory agent. The plant is also used for piles, swellings, rheumatic affections, stiffness of the joints, hemiplegia, and urinary affections. It is the main ingredient of the classical ayurvedic formulation Prasaranadi Kashayam which is used to treat joint pains and Vata diseases. It is mainly used in ayurvedic treatment of joint pain and musculoskeletal problems. The aerial parts contain flavonoids, diometin, luteolin, and 7-O-betaD-glucosides. The objective of the present review is to provide a comprehensive collection of the published information concerning the traditional uses, phytochemistry, and therapeutic potential of M. tridentata.