Phyto-assisted synthesis of zinc oxide nanoparticles using Cassia alata and its antibacterial activity against Escherichia coli

Agarwal Happy; Menon Soumya; S. Venkat Kumar; S. Rajeshkumar; Nakka David Sheba Rani; T. Lakshmi; V. Deepak Nallaswamy

doi:10.1016/j.bbrep.2019.01.002

Phyto-assisted synthesis of zinc oxide nanoparticles using Cassia alata and its antibacterial activity against Escherichia coli

Agarwal Happy
, Menon Soumya
, S. Venkat Kumar
, S. Rajeshkumar
, Nakka David Sheba Rani
, T. Lakshmi
, V. Deepak Nallaswamy

Center of Medical and Bio-allied Health Sciences Research (CMBHSR)

Vellore Institute of Technology
Universiti Brunei Darussalam

Research output: Contribution to journal › Article › peer-review

190 Scopus citations

Abstract

Zinc oxide, an established inorganic metal oxide in nanoparticles form exhibits tremendous anti-bacterial activity. The present study focuses on determining the anti-bacterial activity of green synthesized zinc oxide nanoparticles (ZnO NPs). Results clearly validate the effective synthesis of spherical shaped nanoparticles with average size range of 60–80 nm. SEM and EDAX data buttresses the results obtained by XRD pattern in terms of size and purity. ZnO NPs exhibited dose-dependent anti-bacterial activity against Escherichia coli (E. coli) and the IC₅₀ value was calculated to be around 20 μg/mL. Growth kinetics study was conducted in the presence of nanoparticles which demonstrated the bacteriostatic effect of ZnO NPs. The study recommends the potential use of ZnO NPs in industries like food, pharmaceutical, agriculture, cosmetic industries for its anti-bacterial activity.

Original language	English
Pages (from-to)	208-211
Number of pages	4
Journal	Biochemistry and Biophysics Reports
Volume	17
DOIs	https://doi.org/10.1016/j.bbrep.2019.01.002
State	Published - 2019

Keywords

Anti-bacterial activity
E. coli
Green synthesis
Growth kinetics
Zinc oxide nanoparticles

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10.1016/j.bbrep.2019.01.002

Cite this

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title = "Phyto-assisted synthesis of zinc oxide nanoparticles using Cassia alata and its antibacterial activity against Escherichia coli",

abstract = "Zinc oxide, an established inorganic metal oxide in nanoparticles form exhibits tremendous anti-bacterial activity. The present study focuses on determining the anti-bacterial activity of green synthesized zinc oxide nanoparticles (ZnO NPs). Results clearly validate the effective synthesis of spherical shaped nanoparticles with average size range of 60–80 nm. SEM and EDAX data buttresses the results obtained by XRD pattern in terms of size and purity. ZnO NPs exhibited dose-dependent anti-bacterial activity against Escherichia coli (E. coli) and the IC50 value was calculated to be around 20 μg/mL. Growth kinetics study was conducted in the presence of nanoparticles which demonstrated the bacteriostatic effect of ZnO NPs. The study recommends the potential use of ZnO NPs in industries like food, pharmaceutical, agriculture, cosmetic industries for its anti-bacterial activity.",

keywords = "Anti-bacterial activity, E. coli, Green synthesis, Growth kinetics, Zinc oxide nanoparticles",

author = "Agarwal Happy and Menon Soumya and \{Venkat Kumar\}, S. and S. Rajeshkumar and \{Sheba Rani\}, \{Nakka David\} and T. Lakshmi and \{Deepak Nallaswamy\}, V.",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2019",

doi = "10.1016/j.bbrep.2019.01.002",

language = "English",

volume = "17",

pages = "208--211",

journal = "Biochemistry and Biophysics Reports",

issn = "2405-5808",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Phyto-assisted synthesis of zinc oxide nanoparticles using Cassia alata and its antibacterial activity against Escherichia coli

AU - Happy, Agarwal

AU - Soumya, Menon

AU - Venkat Kumar, S.

AU - Rajeshkumar, S.

AU - Sheba Rani, Nakka David

AU - Lakshmi, T.

AU - Deepak Nallaswamy, V.

PY - 2019

Y1 - 2019

N2 - Zinc oxide, an established inorganic metal oxide in nanoparticles form exhibits tremendous anti-bacterial activity. The present study focuses on determining the anti-bacterial activity of green synthesized zinc oxide nanoparticles (ZnO NPs). Results clearly validate the effective synthesis of spherical shaped nanoparticles with average size range of 60–80 nm. SEM and EDAX data buttresses the results obtained by XRD pattern in terms of size and purity. ZnO NPs exhibited dose-dependent anti-bacterial activity against Escherichia coli (E. coli) and the IC50 value was calculated to be around 20 μg/mL. Growth kinetics study was conducted in the presence of nanoparticles which demonstrated the bacteriostatic effect of ZnO NPs. The study recommends the potential use of ZnO NPs in industries like food, pharmaceutical, agriculture, cosmetic industries for its anti-bacterial activity.

AB - Zinc oxide, an established inorganic metal oxide in nanoparticles form exhibits tremendous anti-bacterial activity. The present study focuses on determining the anti-bacterial activity of green synthesized zinc oxide nanoparticles (ZnO NPs). Results clearly validate the effective synthesis of spherical shaped nanoparticles with average size range of 60–80 nm. SEM and EDAX data buttresses the results obtained by XRD pattern in terms of size and purity. ZnO NPs exhibited dose-dependent anti-bacterial activity against Escherichia coli (E. coli) and the IC50 value was calculated to be around 20 μg/mL. Growth kinetics study was conducted in the presence of nanoparticles which demonstrated the bacteriostatic effect of ZnO NPs. The study recommends the potential use of ZnO NPs in industries like food, pharmaceutical, agriculture, cosmetic industries for its anti-bacterial activity.

KW - Anti-bacterial activity

KW - E. coli

KW - Green synthesis

KW - Growth kinetics

KW - Zinc oxide nanoparticles

UR - https://www.scopus.com/pages/publications/85060515420

U2 - 10.1016/j.bbrep.2019.01.002

DO - 10.1016/j.bbrep.2019.01.002

M3 - Article

AN - SCOPUS:85060515420

SN - 2405-5808

VL - 17

SP - 208

EP - 211

JO - Biochemistry and Biophysics Reports

JF - Biochemistry and Biophysics Reports

ER -

Phyto-assisted synthesis of zinc oxide nanoparticles using Cassia alata and its antibacterial activity against Escherichia coli

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Keywords

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