PARP1-PROTACs providing novel opportunities in precision oncology by targeting DNA damage response

Md Sadique Hussain; Gaurav Gupta

doi:10.1016/j.dnarep.2025.103851

PARP1-PROTACs providing novel opportunities in precision oncology by targeting DNA damage response

Md Sadique Hussain
, Gaurav Gupta

Center of Medical and Bio-allied Health Sciences Research (CMBHSR)

Uttaranchal University
Chitkara University

Research output: Contribution to journal › Letter › peer-review

3 Scopus citations

Original language	English
Article number	103851
Journal	DNA Repair
Volume	150
DOIs	https://doi.org/10.1016/j.dnarep.2025.103851
State	Published - Jun 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer therapeutics
DNA repair
E3 Ubiquitin
Olaparib
Proteolysis-targeting chimeras
Targeted protein degradation

Access to Document

10.1016/j.dnarep.2025.103851

Cite this

@article{80243ed5cea0460e9c687499829958e0,

title = "PARP1-PROTACs providing novel opportunities in precision oncology by targeting DNA damage response",

keywords = "Cancer therapeutics, DNA repair, E3 Ubiquitin, Olaparib, Proteolysis-targeting chimeras, Targeted protein degradation",

author = "Hussain, \{Md Sadique\} and Gaurav Gupta",

year = "2025",

month = jun,

doi = "10.1016/j.dnarep.2025.103851",

language = "English",

volume = "150",

journal = "DNA Repair",

issn = "1568-7864",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - PARP1-PROTACs providing novel opportunities in precision oncology by targeting DNA damage response

AU - Hussain, Md Sadique

AU - Gupta, Gaurav

PY - 2025/6

Y1 - 2025/6

KW - Cancer therapeutics

KW - DNA repair

KW - E3 Ubiquitin

KW - Olaparib

KW - Proteolysis-targeting chimeras

KW - Targeted protein degradation

UR - https://www.scopus.com/pages/publications/105006681990

U2 - 10.1016/j.dnarep.2025.103851

DO - 10.1016/j.dnarep.2025.103851

M3 - Letter

C2 - 40440930

AN - SCOPUS:105006681990

SN - 1568-7864

VL - 150

JO - DNA Repair

JF - DNA Repair

M1 - 103851

ER -

PARP1-PROTACs providing novel opportunities in precision oncology by targeting DNA damage response

UN SDGs

Keywords

Access to Document

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