Oral antimicrobial peptides: Types and role in the oral cavity

Zohaib Khurshid; Mustafa Naseem; Zeeshan Sheikh; Shariq Najeeb; Sana Shahab; Muhammad Sohail Zafar

doi:10.1016/j.jsps.2015.02.015

Oral antimicrobial peptides: Types and role in the oral cavity

Zohaib Khurshid
, Mustafa Naseem
, Zeeshan Sheikh
, Shariq Najeeb
, Sana Shahab
, Muhammad Sohail Zafar

University of Birmingham
Ziauddin University
University of Toronto
Al-Farabi Colleges
Sir Syed College of Medical Sciences for Girls
Taibah University

Research output: Contribution to journal › Review article › peer-review

154 Scopus citations

Abstract

Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.

Original language	English
Pages (from-to)	515-524
Number of pages	10
Journal	Saudi Pharmaceutical Journal
Volume	24
Issue number	5
DOIs	https://doi.org/10.1016/j.jsps.2015.02.015
State	Published - 1 Sep 2016
Externally published	Yes

Keywords

Antimicrobial peptides (AMPs)
Cathelicidins
Defensins
Dental applications
Histatins
Oral cavity

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10.1016/j.jsps.2015.02.015

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title = "Oral antimicrobial peptides: Types and role in the oral cavity",

abstract = "Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.",

keywords = "Antimicrobial peptides (AMPs), Cathelicidins, Defensins, Dental applications, Histatins, Oral cavity",

author = "Zohaib Khurshid and Mustafa Naseem and Zeeshan Sheikh and Shariq Najeeb and Sana Shahab and Zafar, \{Muhammad Sohail\}",

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TY - JOUR

T1 - Oral antimicrobial peptides

T2 - Types and role in the oral cavity

AU - Khurshid, Zohaib

AU - Naseem, Mustafa

AU - Sheikh, Zeeshan

AU - Najeeb, Shariq

AU - Shahab, Sana

AU - Zafar, Muhammad Sohail

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.

AB - Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.

KW - Antimicrobial peptides (AMPs)

KW - Cathelicidins

KW - Defensins

KW - Dental applications

KW - Histatins

KW - Oral cavity

UR - https://www.scopus.com/pages/publications/84924778450

U2 - 10.1016/j.jsps.2015.02.015

DO - 10.1016/j.jsps.2015.02.015

M3 - Review article

AN - SCOPUS:84924778450

SN - 1319-0164

VL - 24

SP - 515

EP - 524

JO - Saudi Pharmaceutical Journal

JF - Saudi Pharmaceutical Journal

IS - 5

ER -

Oral antimicrobial peptides: Types and role in the oral cavity

Abstract

Keywords

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