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Nutrition, Epigenetics, and Stem Cells

  • Linköping University

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Stem cells represent the regenerative capacity of our bodies; hence, it is essential for these cells to interact with the intrinsic and extrinsic environments, including nutritional components. Stem cells receive the nutritional elements as signal molecules that transmit certain messages to the cell epigenome, leading to cell differentiation. Such an effect could be similarly induced using several epigenetic modifiers. The influence of nutritional elements and contaminants on differentiation were demonstrated on embryonic stem cells during the embryonic development, as well as through in vitro studies. Similar evidence can be illustrated for adult stem cells in laboratory experiments. The interaction between nutrition and epigenetic can exert their effects on stem cell plasticity and differentiation, which may help in maintaining our health status and help in tissue regeneration after disease. This chapter includes an overview of the interaction between nutrition and stem cells through epigenetic mechanisms.

Original languageEnglish
Title of host publicationEpigenetics and Human Health
PublisherSpringer Science and Business Media Deutschland GmbH
Pages105-119
Number of pages15
DOIs
StatePublished - 2024

Publication series

NameEpigenetics and Human Health
Volume12
ISSN (Print)2191-2262
ISSN (Electronic)2191-2270

Keywords

  • Contaminants
  • DNA methylation
  • Differentiation
  • Epigenetic
  • Epigenetic modifier
  • Histone
  • Microbiota
  • Nutrition
  • Stem cells

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