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Numerical study and dynamics analysis of diabetes mellitus with co-infection of COVID-19 virus by using fractal fractional operator

  • Muhammad Farman
  • , Ali Akgül
  • , Muhammad Sultan
  • , Sidra Riaz
  • , Hira Asif
  • , Praveen Agarwal
  • , Murad Khan Hassani
  • Near East University
  • Lebanese American University
  • Siirt University
  • Georgian College
  • International College of Engineering
  • Ghazni University

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

COVID-19 is linked to diabetes, increasing the likelihood and severity of outcomes due to hyperglycemia, immune system impairment, vascular problems, and comorbidities like hypertension, obesity, and cardiovascular disease, which can lead to catastrophic outcomes. The study presents a novel COVID-19 management approach for diabetic patients using a fractal fractional operator and Mittag-Leffler kernel. It uses the Lipschitz criterion and linear growth to identify the solution singularity and analyzes the global derivative impact, confirming unique solutions and demonstrating the bounded nature of the proposed system. The study examines the impact of COVID-19 on individuals with diabetes, using global stability analysis and quantitative examination of equilibrium states. Sensitivity analysis is conducted using reproductive numbers to determine the disease’s status in society and the impact of control strategies, highlighting the importance of understanding epidemic problems and their properties. This study uses two-step Lagrange polynomial to analyze the impact of the fractional operator on a proposed model. Numerical simulations using MATLAB validate the effects of COVID-19 on diabetic patients and allow predictions based on the established theoretical framework, supporting the theoretical findings. This study will help to observe and understand how COVID-19 affects people with diabetes. This will help with control plans in the future to lessen the effects of COVID-19.

Original languageEnglish
Article number16489
JournalScientific Reports
Volume14
Issue number1
DOIs
StatePublished - Dec 2024
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • COVID-19
  • Diabetes
  • Fractal–fractional operator
  • Mittg-Leffler kernel

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