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Numerical Solution for Fuzzy Time-Fractional Cancer Tumor Model with a Time-Dependent Net Killing Rate of Cancer Cells

  • Hamzeh Zureigat
  • , Mohammed Al-Smadi
  • , Areen Al-Khateeb
  • , Shrideh Al-Omari
  • , Sharifah Alhazmi
  • Jadara University
  • Lusail University
  • Al-Balqa Applied University
  • Umm Al-Qura University

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A cancer tumor model is an important tool for studying the behavior of various cancer tumors. Recently, many fuzzy time-fractional diffusion equations have been employed to describe cancer tumor models in fuzzy conditions. In this paper, an explicit finite difference method has been developed and applied to solve a fuzzy time-fractional cancer tumor model. The impact of using the fuzzy time-fractional derivative has been examined under the double parametric form of fuzzy numbers rather than using classical time derivatives in fuzzy cancer tumor models. In addition, the stability of the proposed model has been investigated by applying the Fourier method, where the net killing rate of the cancer cells is only time-dependent, and the time-fractional derivative is Caputo’s derivative. Moreover, certain numerical experiments are discussed to examine the feasibility of the new approach and to check the related aspects. Over and above, certain needs in studying the fuzzy fractional cancer tumor model are detected to provide a better comprehensive understanding of the behavior of the tumor by utilizing several fuzzy cases on the initial conditions of the proposed model.

Original languageEnglish
Article number3766
JournalInternational Journal of Environmental Research and Public Health
Volume20
Issue number4
DOIs
StatePublished - Feb 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Caputo formula
  • cancer tumor models
  • finite difference scheme
  • fuzzy fractional diffusion equation

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