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Numerical investigation of a fractional model of a tumor-immune surveillance via Caputo operator

  • Saleh Alshammari
  • , Mohammad Alshammari
  • , Mohammed Alabedalhadi
  • , M. Mossa Al-Sawalha
  • , Mohammed Al-Smadi
  • University of Hail
  • Al-Balqa Applied University
  • Lusail University

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Fractional calculus has become a potent tool for simulating the complexity of interactions in tumor-immune system dynamics. This paper investigates the existence and uniqueness of its approximation solutions of a fractional model of tumor-immune surveillance. This analysis is essential for proving the validity and dependability of the model and provides a more in-depth understanding of the dynamics of the tumor-immune surveillance system. Second, we examine the fractional model's numerical features. We utilize a numerical technique called the Laplace residual power series method to address the equations' complexity and nonlinearity. By defining the answers as a fractional power series, this method enables us to efficiently approximate the solutions. The use of this technique enables us to investigate the temporal evolution of the tumor-immune system, offering important insights into the stability and behavior of the system. We assess the effectiveness of the Laplace residual power series method in locating approximations through a series of thorough numerical simulations. To ensure the correctness and dependability of our method, we compare the numerical findings whenever possible with well-known analytical solutions.

Original languageEnglish
Pages (from-to)525-536
Number of pages12
JournalAlexandria Engineering Journal
Volume86
DOIs
StatePublished - Jan 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cancer treatment
  • Fractional calculus
  • Laplace residual power series method
  • Tumor-immune surveillance

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