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Nanoparticle-based drug delivery for chronic obstructive pulmonary disorder and asthma

  • Ridhima Wadhwa
  • , Taru Aggarwal
  • , Noopur Thapliyal
  • , Dinesh Kumar Chellappan
  • , Gaurav Gupta
  • , Monica Gulati
  • , Trudi Collet
  • , Brian Oliver
  • , Kylie Williams
  • , Philip Michael Hansbro
  • , Kamal Dua
  • , Pawan Kumar Maurya
  • South Asian University
  • Amity University, Noida
  • International Medical University
  • University of Allahabad
  • Universidade Estadual de Campinas
  • Queensland University of Technology
  • University of Technology Sydney
  • Centre for InflammationCentenary Institute
  • Hunter Medical Research Institute, Australia
  • Central University of Haryana

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

27 Scopus citations

Abstract

Pulmonary diseases including chronic obstructive pulmonary disease (COPD) and asthma affect millions of people all over the world. Conventional treatment methodologies are not sufficient to cure or prevent the disease. With the advent of nanotechnology, drug delivery to specific target site is still challenging, but targeted delivery can be achieved by physiochemical properties of the nanoparticles. Delivery of nanoparticles, liposomes, dendrimers, and others has been extensively studied for successful delivery by inhalation and aerosols. Several factors such as size, density, surface, and physical-chemical properties of nanoparticle are essential to cross airway barriers. In this chapter, different nanoparticle-mediated drug delivery systems have been highlighted along with their applications and toxicity in COPD and asthma.

Original languageEnglish
Title of host publicationNanotechnology in Modern Animal Biotechnology
Subtitle of host publicationConcepts and Applications
PublisherElsevier
Pages59-73
Number of pages15
ISBN (Electronic)9780128188231
DOIs
StatePublished - 1 Jan 2019
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Asthma
  • Chronic obstructive pulmonary disease
  • Nanoparticles
  • Therapeutics
  • Toxicity

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