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Nanoneuroscience: Cutting-edge Approach for Disease Management

  • Sakshi Malhotra
  • , Neha Jain
  • , Jatin Rathee
  • , Shreya Kaul
  • , Upendra Nagaich
  • , Manisha Pandey
  • , Bapi Gorain
  • , Gaurav Gupta
  • Amity University, Noida
  • International Medical University
  • Central University of Haryana
  • Birla Institute of Technology, Mesra
  • Suresh Gyan Vihar University
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)
  • Uttaranchal University

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Neurological disorders (ND) have affected a major part of our society and have been a challenge for medical and biosciences for decades. However, many of these disorders haven't responded well to currently established treatment approaches. The fact that many active pharmaceutical ingredients can't get to their specified action site inside the body is one of the main reasons for this failure. Extracellular and intracellular central nervous system (CNS) barriers prevent the transfer of drugs from the blood circulation to the intended location of the action. Utilizing nanosized drug delivery technologies is one possible way to overcome these obstacles. These nano-drug carriers outperform conventional dosage forms in many areas, including good drug encapsulation capacity, targeted drug delivery, less toxicity, and enhanced therapeutic impact. As a result, nano-neuroscience is growing to be an intriguing area of research and a bright alternative approach for delivering medicines to their intended action site for treating different neurological and psychiatric problems. In this review, we have included a short overview of the pathophysiology of neurological diseases, a detailed discussion about the significance of nanocarriers in NDs, and a focus on its recent advances. Finally, we highlighted the patented technologies and market trends, including the predictive analysis for the years 2021-2028.

Original languageEnglish
Pages (from-to)305-320
Number of pages16
JournalRecent Patents on Nanotechnology
Volume18
Issue number3
DOIs
StatePublished - 2024
Externally publishedYes

Keywords

  • Nose to brain targeting
  • carbon-based nanomaterials
  • central nervous system (cns)
  • market trends
  • nanoparticles
  • patents

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