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Molecular and genetic aspects of odontogenic tumors: A review

  • Kavita Garg
  • , Shaleen Chandra
  • , Vineet Raj
  • , Wamiq Fareed
  • , Muhammad Zafar
  • Chandra Dental College
  • Saraswati Dental College and Hospital
  • King George's Medical University
  • Taibah University

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Odontogenic tumors contain a heterogeneous collection of lesions that are categorized from hamartomas to benign and malignant neoplasms of inconstant aggressiveness. Odontogenic tumors are usually extraordinary with assessed frequency of short of 0.5 cases/100,000 population for every year. The lesions such as odontogenic tumors are inferred from the components of the toothstructuring contraption. They are discovered solely inside the maxillary and mandibular bones. This audit speaks to experiences and cooperation of the molecular and genetic variations connected to the development and movement of odontogenic tumors which incorporate oncogenes, tumor‐silencer genes, APC gene, retinoblastoma genes, DNA repair genes, onco‐viruses, development components, telomerase, cell cycle controllers, apoptosis‐related elements, and regulators/controllers of tooth development. The reasonable and better understanding of the molecular components may prompt new ideas for their detection and administrating a better prognosis of odontogenic tumors.

Original languageEnglish
Pages (from-to)529-536
Number of pages8
JournalIranian Journal of Basic Medical Sciences
Volume18
Issue number6
StatePublished - 1 Jun 2015
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Genes
  • Odontogenesis
  • Odontogenic tumors

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