Modern Perspectives of Ultrasound-Based Drug Delivery

Kaustubh Ajit Kolekar; Sukriti Vishwas; Sachin Kumar Singh; Popat S. Kumbhar; Vaishali Yadav; Kalpana S. Patil; Kamal Dua; John Disouza; Vandana B. Patravale

doi:10.1007/978-981-96-6275-3_4

Modern Perspectives of Ultrasound-Based Drug Delivery

Kaustubh Ajit Kolekar
, Sukriti Vishwas
, Sachin Kumar Singh
, Popat S. Kumbhar
, Vaishali Yadav
, Kalpana S. Patil
, Kamal Dua
, John Disouza
, Vandana B. Patravale

Lovely Professional University
University of Technology Sydney
Shivaji University
SYBES’s Bombay Institute of Pharmacy and Research
Institute of Chemical Technology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Scopus citations

Abstract

Ultrasound-based drug delivery is a transformative approach that enhances the efficacy and precision of therapeutic agents. It improves the delivery of drugs through diverse mechanisms including cavitations, acoustic streaming, sonoporation, and thermal effects. This method enables targeted delivery, reduces side effects, and offers versatile, noninvasive applications. This chapter discusses ultrasound technology fundamentals, including hyperthermia and acoustic streaming, which facilitate drug transport. Additionally, the chapter focuses on recent advancements including smart drug delivery systems like liposomes, polymers, and microbubbles that respond to ultrasound for modified release. Moreover, potential applications of ultrasound-mediated drug delivery systems for managing various diseases are also discussed. Further, challenges regarding safety, optimal ultrasound parameters, and delivery efficiency are briefed. Overall, ultrasound technology has the potential to revolutionize drug delivery, paving the way for innovative therapies. Further investigation is needed to address present constraints and optimize its clinical application.

Original language	English
Title of host publication	Transdermal Applications of Minimally Invasive Drug Delivery Systems
Subtitle of host publication	Current Trends and Future Perspectives
Publisher	Springer Science+Business Media
Pages	73-92
Number of pages	20
ISBN (Electronic)	9789819662753
ISBN (Print)	9789819662746
DOIs	https://doi.org/10.1007/978-981-96-6275-3_4
State	Published - 1 Jan 2025
Externally published	Yes

Keywords

Combination therapies
Diseases
Mechanisms
Smart drug delivery systems
Sonophoresis
Ultrasound-based drug delivery

Access to Document

10.1007/978-981-96-6275-3_4

Cite this

Ajit Kolekar, K., Vishwas, S., Kumar Singh, S., Kumbhar, P. S., Yadav, V., Patil, K. S., Dua, K., Disouza, J., & Patravale, V. B. (2025). Modern Perspectives of Ultrasound-Based Drug Delivery. In Transdermal Applications of Minimally Invasive Drug Delivery Systems: Current Trends and Future Perspectives (pp. 73-92). Springer Science+Business Media. https://doi.org/10.1007/978-981-96-6275-3_4

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abstract = "Ultrasound-based drug delivery is a transformative approach that enhances the efficacy and precision of therapeutic agents. It improves the delivery of drugs through diverse mechanisms including cavitations, acoustic streaming, sonoporation, and thermal effects. This method enables targeted delivery, reduces side effects, and offers versatile, noninvasive applications. This chapter discusses ultrasound technology fundamentals, including hyperthermia and acoustic streaming, which facilitate drug transport. Additionally, the chapter focuses on recent advancements including smart drug delivery systems like liposomes, polymers, and microbubbles that respond to ultrasound for modified release. Moreover, potential applications of ultrasound-mediated drug delivery systems for managing various diseases are also discussed. Further, challenges regarding safety, optimal ultrasound parameters, and delivery efficiency are briefed. Overall, ultrasound technology has the potential to revolutionize drug delivery, paving the way for innovative therapies. Further investigation is needed to address present constraints and optimize its clinical application.",

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author = "\{Ajit Kolekar\}, Kaustubh and Sukriti Vishwas and \{Kumar Singh\}, Sachin and Kumbhar, \{Popat S.\} and Vaishali Yadav and Patil, \{Kalpana S.\} and Kamal Dua and John Disouza and Patravale, \{Vandana B.\}",

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Ajit Kolekar, K, Vishwas, S, Kumar Singh, S, Kumbhar, PS, Yadav, V, Patil, KS, Dua, K, Disouza, J & Patravale, VB 2025, Modern Perspectives of Ultrasound-Based Drug Delivery. in Transdermal Applications of Minimally Invasive Drug Delivery Systems: Current Trends and Future Perspectives. Springer Science+Business Media, pp. 73-92. https://doi.org/10.1007/978-981-96-6275-3_4

Modern Perspectives of Ultrasound-Based Drug Delivery. / Ajit Kolekar, Kaustubh; Vishwas, Sukriti; Kumar Singh, Sachin et al.
Transdermal Applications of Minimally Invasive Drug Delivery Systems: Current Trends and Future Perspectives. Springer Science+Business Media, 2025. p. 73-92.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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Modern Perspectives of Ultrasound-Based Drug Delivery

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Keywords

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