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Modeling the SARS-CoV-2 parallel transmission dynamics: Asymptomatic and symptomatic pathways

  • S. M.E.K. Chowdhury
  • , Mohammad Forkan
  • , Shams Forruque Ahmed
  • , Praveen Agarwal
  • , A. B.M. Shawkat Ali
  • , S. M. Muyeen
  • University of Chittagong
  • Asian University for Women
  • International College of Engineering
  • International Center for Basic and Applied Sciences
  • Central Queensland University
  • The University of Fiji
  • Department of Electrical Engineering, Qatar University

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Asymptomatic transmission of the coronavirus disease and the infected individual prediction has become very important in the COVID-19 outbreak study. The asymptomatic and symptomatic transmission studies are still ongoing to assess their impacts on disease monitoring and burden. However, there has been limited research on how asymptomatic and symptomatic transmissions together can affect the coronavirus disease outbreak. A mathematical model is therefore needed to be developed in order to assess the effect of these transmissions on the coronavirus disease dynamics. This paper develops a mathematical model concerning asymptomatic and symptomatic disease transmission processes in the COVID-19 outbreak. The model sensitivity has been analysed in terms of the variance of each parameter, and the local stability at two equilibrium points have been discussed in terms of the basic reproduction number (R0). It is found that the disease-free equilibrium gets stable for R0 < 1 whereas the endemic equilibrium becomes stable for R0 > 1 and unstable otherwise. The proportion of the effect of asymptomatic and symptomatic transmission rates on R0 is calculated to be approximately between 1 and 3. The results demonstrate that asymptomatic transmission has a significant impact compared to symptomatic transmission in the disease outbreak. Outcomes of this study will contribute to setting an effective control strategy for the COVID-19 outbreak.

Original languageEnglish
Article number105264
JournalComputers in Biology and Medicine
Volume143
DOIs
StatePublished - Apr 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Asymptomatic transmission
  • Basic reproduction number
  • COVID-19
  • Mathematical model
  • SARS-CoV-2
  • Symptomatic transmission

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