Abstract
Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.
| Original language | English |
|---|---|
| Pages (from-to) | 3298-3322 |
| Number of pages | 25 |
| Journal | International Journal of Molecular Sciences |
| Volume | 11 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 2010 |
| Externally published | Yes |
Keywords
- Biodegradable
- Biomaterials
- Copolymers
- Manufacture
- Microparticle
- Nanoparticle
- Particle engineering design
- Pharmaceutical dosage forms
- Polymers
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