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Ionizing and nonionizing radiation linked to lung cancer

  • Asif Ahmad Bhat
  • , Muhammad Afzal
  • , Riya Thapa
  • , Md Sadique Hussain
  • , Riya Mishra
  • , Abdullah Khan
  • , B. Tazneem
  • , S. Roshan
  • , Gaurav Gupta
  • , Vanaja Kenchappa
  • Uttaranchal University
  • Batterjee Medical College
  • Suresh Gyan Vihar University
  • Quest International University Perak
  • Osmania University
  • Chitkara University
  • Dayananda Sagar Institutions

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

This book chapter aims to explore the relationship between ionizing and nonionizing radiation and lung cancer. The interaction between radiation types and the cellular and genetic level is discussed in this context, leading to possible carcinogenesis. In this respect, there is a plethora of evidence supporting the association between ionizing radiation that damages the DNA molecule directly or destroys paternal structures and the increased risk of lung cancer. Thus this chapter discusses the epidemiological evidence and provides the example of atomic bomb survivors and radiotherapy patients where the dose-related risks are described. As for nonionizing radiation, including radiation related to mobile phones and other RF-EMF-emitting sources, the evidence for lung cancer origin is limited. Despite the lack of ionization capability, scientists propose long-term biological effects due to possible mechanisms, including thermal and oxidative stress. Thus the findings of this chapter, the ongoing debates, and the limitations of the research methodology on the potential effects of nonionizing radiation are used. Moreover, the chapter describes potential recommendations for radiation exposure, possible implications of the novel technology, and directions for further research. Thus this synthesis may help readers understand the risk of radiation exposure prevention measures that can decrease it and imply them while creating policies and regulations to prevent radiation-induced lung cancer.

Original languageEnglish
Title of host publicationLung Cancer and Environmental Toxicants
PublisherElsevier
Pages237-255
Number of pages19
ISBN (Electronic)9780443301209
ISBN (Print)9780443301216
DOIs
StatePublished - 1 Jan 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Damage
  • cancer systems biology
  • carcinogenesis
  • electromagnetic fields
  • epidemiology
  • ionizing radiation
  • lung cancer
  • nonionizing radiation
  • oncology
  • pathology
  • prevention
  • radiofrequency radiation
  • radon
  • respiratory system disease
  • risk assessment
  • therapeutic procedure
  • toxicity

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