Introduction to cancer cell biology

Mohammad Arshad Shaikh; Ritu Gilhotra; Santosh Kumar Singh; Sushma Rawat; Gaurav Gupta; Salman Hussain; Yogendra Singh; Saurabh Satija; Meenu Mehta; Kamal Dua

doi:10.1016/B978-0-323-85503-7.00013-4

Introduction to cancer cell biology

Mohammad Arshad Shaikh
, Ritu Gilhotra
, Santosh Kumar Singh
, Sushma Rawat
, Gaurav Gupta
, Salman Hussain
, Yogendra Singh
, Saurabh Satija
, Meenu Mehta
, Kamal Dua

R P College of Pharmacy
Suresh Gyan Vihar University
School of Pharmaceutical Education and Research
Maharishi Arvind College of Pharmacy
University of Technology Sydney
Lovely Professional University

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

Cancer comprises more than 200 genetically related diseases in which information about cells stored in DNA is altered, resulting in changes in gene expression and abnormal cell development, proliferation, and metastasis. Genetic factors, environmental factors, lifestyle factors, occupations, and certain biological factors play a crucial role in the development of various types of cancer. There are eight distinguishing and harmonizing features or hallmarks of cancer cells. These include sustained multiplication (proliferative) signaling, avoidance of immune annihilation (destruction), deregulation of cell energetics, avoidance of apoptosis, shunning of anti-growth signals, metastasis and tissue invasion, endless multiplication (replication) potential, and extended (sustained) tumor angiogenesis. There are two characteristics that enable tumor growth and metastasis: genetic instability and mutability, and inflammation.

Original language	English
Title of host publication	Advanced Drug Delivery Systems in the Management of Cancer
Publisher	Elsevier
Pages	1-7
Number of pages	7
ISBN (Electronic)	9780323855037
ISBN (Print)	9780323900799
DOIs	https://doi.org/10.1016/B978-0-323-85503-7.00013-4
State	Published - 1 Jan 2021
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer
Diagnosis
Lifestyle
Mutation
Tumor

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10.1016/B978-0-323-85503-7.00013-4

Cite this

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title = "Introduction to cancer cell biology",

abstract = "Cancer comprises more than 200 genetically related diseases in which information about cells stored in DNA is altered, resulting in changes in gene expression and abnormal cell development, proliferation, and metastasis. Genetic factors, environmental factors, lifestyle factors, occupations, and certain biological factors play a crucial role in the development of various types of cancer. There are eight distinguishing and harmonizing features or hallmarks of cancer cells. These include sustained multiplication (proliferative) signaling, avoidance of immune annihilation (destruction), deregulation of cell energetics, avoidance of apoptosis, shunning of anti-growth signals, metastasis and tissue invasion, endless multiplication (replication) potential, and extended (sustained) tumor angiogenesis. There are two characteristics that enable tumor growth and metastasis: genetic instability and mutability, and inflammation.",

keywords = "Cancer, Diagnosis, Lifestyle, Mutation, Tumor",

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T1 - Introduction to cancer cell biology

AU - Shaikh, Mohammad Arshad

AU - Gilhotra, Ritu

AU - Singh, Santosh Kumar

AU - Rawat, Sushma

AU - Gupta, Gaurav

AU - Hussain, Salman

AU - Singh, Yogendra

AU - Satija, Saurabh

AU - Mehta, Meenu

AU - Dua, Kamal

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Cancer comprises more than 200 genetically related diseases in which information about cells stored in DNA is altered, resulting in changes in gene expression and abnormal cell development, proliferation, and metastasis. Genetic factors, environmental factors, lifestyle factors, occupations, and certain biological factors play a crucial role in the development of various types of cancer. There are eight distinguishing and harmonizing features or hallmarks of cancer cells. These include sustained multiplication (proliferative) signaling, avoidance of immune annihilation (destruction), deregulation of cell energetics, avoidance of apoptosis, shunning of anti-growth signals, metastasis and tissue invasion, endless multiplication (replication) potential, and extended (sustained) tumor angiogenesis. There are two characteristics that enable tumor growth and metastasis: genetic instability and mutability, and inflammation.

AB - Cancer comprises more than 200 genetically related diseases in which information about cells stored in DNA is altered, resulting in changes in gene expression and abnormal cell development, proliferation, and metastasis. Genetic factors, environmental factors, lifestyle factors, occupations, and certain biological factors play a crucial role in the development of various types of cancer. There are eight distinguishing and harmonizing features or hallmarks of cancer cells. These include sustained multiplication (proliferative) signaling, avoidance of immune annihilation (destruction), deregulation of cell energetics, avoidance of apoptosis, shunning of anti-growth signals, metastasis and tissue invasion, endless multiplication (replication) potential, and extended (sustained) tumor angiogenesis. There are two characteristics that enable tumor growth and metastasis: genetic instability and mutability, and inflammation.

KW - Cancer

KW - Diagnosis

KW - Lifestyle

KW - Mutation

KW - Tumor

UR - https://www.scopus.com/pages/publications/85135658518

U2 - 10.1016/B978-0-323-85503-7.00013-4

DO - 10.1016/B978-0-323-85503-7.00013-4

M3 - Chapter

AN - SCOPUS:85135658518

SN - 9780323900799

SP - 1

EP - 7

BT - Advanced Drug Delivery Systems in the Management of Cancer

PB - Elsevier

ER -

Introduction to cancer cell biology

Abstract

UN SDGs

Keywords

Access to Document

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