In-vitro antibacterial efficacy of propolis against E. faecalis as compared to other intracanal medicaments: A systematic review and meta-analysis

Juzer Shabbir; Zohaib Khurshid; Waqas Farooqui; Muhammad Sohail Zafar; Huma Sarwar; Eisha Imran; Syed Masood ul Hasan

doi:10.1016/j.hermed.2023.100673

In-vitro antibacterial efficacy of propolis against E. faecalis as compared to other intracanal medicaments: A systematic review and meta-analysis

Juzer Shabbir
, Zohaib Khurshid
, Waqas Farooqui
, Muhammad Sohail Zafar
, Huma Sarwar
, Eisha Imran
, Syed Masood ul Hasan

Liaquat College of Medicine and Dentistry
Baqai Medical University
King Faisal University
Chulalongkorn University
Dow University of Health Sciences
Taibah University
Riphah International University
Islamabad Medical and Dental College

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Objectives: To evaluate the antibacterial efficacy of propolis against Enterococcus faecalis (E. faecalis) compared to other intracanal medicaments (ICM). Material and methods: Experimental papers related to the objective of the study, published from September 2006 to October 2020 were identified at Medline, Scopus, and Web of Science platforms, and screened. A total of 19 studies were included in the systematic review (SR) and 9 in meta-analysis. Colony Forming Units (CFU) in Propolis group was compared with Calcium hydroxide (Ca(OH)2), Chlorhexidine (CHX), and Saline through meta-analysis (Stata software). Results: A total of 19 studies were included in the systematic review and 9 in meta-analysis. Systematic review indicated that CHX and Triple Antibiotic Paste (TAP) had higher antibacterial efficacy as compared to Propolis and Ca(OH)₂. The meta-analysis suggested that Propolis had significantly lower CFU count as compared to Ca(OH)₂ and Saline (p < 0.05), and higher as compared to CHX (p < 0.05). Conclusions: Propolis had a higher antibacterial efficacy compared to Ca(OH)₂ and saline, and a lower antibacterial efficacy compared to CHX.

Original language	English
Article number	100673
Journal	Journal of Herbal Medicine
Volume	40
DOIs	https://doi.org/10.1016/j.hermed.2023.100673
State	Published - Aug 2023
Externally published	Yes

Keywords

Calcium hydroxide
Chlorhexidine
E. faecalis
Intracanal medicament
Propolis
Root canal treatment
Saline

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10.1016/j.hermed.2023.100673

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@article{8feb1b9498714852b353647475b92838,

title = "In-vitro antibacterial efficacy of propolis against E. faecalis as compared to other intracanal medicaments: A systematic review and meta-analysis",

abstract = "Objectives: To evaluate the antibacterial efficacy of propolis against Enterococcus faecalis (E. faecalis) compared to other intracanal medicaments (ICM). Material and methods: Experimental papers related to the objective of the study, published from September 2006 to October 2020 were identified at Medline, Scopus, and Web of Science platforms, and screened. A total of 19 studies were included in the systematic review (SR) and 9 in meta-analysis. Colony Forming Units (CFU) in Propolis group was compared with Calcium hydroxide (Ca(OH)2), Chlorhexidine (CHX), and Saline through meta-analysis (Stata software). Results: A total of 19 studies were included in the systematic review and 9 in meta-analysis. Systematic review indicated that CHX and Triple Antibiotic Paste (TAP) had higher antibacterial efficacy as compared to Propolis and Ca(OH)2. The meta-analysis suggested that Propolis had significantly lower CFU count as compared to Ca(OH)2 and Saline (p < 0.05), and higher as compared to CHX (p < 0.05). Conclusions: Propolis had a higher antibacterial efficacy compared to Ca(OH)2 and saline, and a lower antibacterial efficacy compared to CHX.",

keywords = "Calcium hydroxide, Chlorhexidine, E. faecalis, Intracanal medicament, Propolis, Root canal treatment, Saline",

author = "Juzer Shabbir and Zohaib Khurshid and Waqas Farooqui and Zafar, \{Muhammad Sohail\} and Huma Sarwar and Eisha Imran and \{ul Hasan\}, \{Syed Masood\}",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier GmbH",

year = "2023",

month = aug,

doi = "10.1016/j.hermed.2023.100673",

language = "English",

volume = "40",

journal = "Journal of Herbal Medicine",

issn = "2210-8033",

publisher = "Elsevier GmbH",

}

TY - JOUR

T1 - In-vitro antibacterial efficacy of propolis against E. faecalis as compared to other intracanal medicaments

T2 - A systematic review and meta-analysis

AU - Shabbir, Juzer

AU - Khurshid, Zohaib

AU - Farooqui, Waqas

AU - Zafar, Muhammad Sohail

AU - Sarwar, Huma

AU - Imran, Eisha

AU - ul Hasan, Syed Masood

PY - 2023/8

Y1 - 2023/8

N2 - Objectives: To evaluate the antibacterial efficacy of propolis against Enterococcus faecalis (E. faecalis) compared to other intracanal medicaments (ICM). Material and methods: Experimental papers related to the objective of the study, published from September 2006 to October 2020 were identified at Medline, Scopus, and Web of Science platforms, and screened. A total of 19 studies were included in the systematic review (SR) and 9 in meta-analysis. Colony Forming Units (CFU) in Propolis group was compared with Calcium hydroxide (Ca(OH)2), Chlorhexidine (CHX), and Saline through meta-analysis (Stata software). Results: A total of 19 studies were included in the systematic review and 9 in meta-analysis. Systematic review indicated that CHX and Triple Antibiotic Paste (TAP) had higher antibacterial efficacy as compared to Propolis and Ca(OH)2. The meta-analysis suggested that Propolis had significantly lower CFU count as compared to Ca(OH)2 and Saline (p < 0.05), and higher as compared to CHX (p < 0.05). Conclusions: Propolis had a higher antibacterial efficacy compared to Ca(OH)2 and saline, and a lower antibacterial efficacy compared to CHX.

AB - Objectives: To evaluate the antibacterial efficacy of propolis against Enterococcus faecalis (E. faecalis) compared to other intracanal medicaments (ICM). Material and methods: Experimental papers related to the objective of the study, published from September 2006 to October 2020 were identified at Medline, Scopus, and Web of Science platforms, and screened. A total of 19 studies were included in the systematic review (SR) and 9 in meta-analysis. Colony Forming Units (CFU) in Propolis group was compared with Calcium hydroxide (Ca(OH)2), Chlorhexidine (CHX), and Saline through meta-analysis (Stata software). Results: A total of 19 studies were included in the systematic review and 9 in meta-analysis. Systematic review indicated that CHX and Triple Antibiotic Paste (TAP) had higher antibacterial efficacy as compared to Propolis and Ca(OH)2. The meta-analysis suggested that Propolis had significantly lower CFU count as compared to Ca(OH)2 and Saline (p < 0.05), and higher as compared to CHX (p < 0.05). Conclusions: Propolis had a higher antibacterial efficacy compared to Ca(OH)2 and saline, and a lower antibacterial efficacy compared to CHX.

KW - Calcium hydroxide

KW - Chlorhexidine

KW - E. faecalis

KW - Intracanal medicament

KW - Propolis

KW - Root canal treatment

KW - Saline

UR - https://www.scopus.com/pages/publications/85161602192

U2 - 10.1016/j.hermed.2023.100673

DO - 10.1016/j.hermed.2023.100673

M3 - Review article

AN - SCOPUS:85161602192

SN - 2210-8033

VL - 40

JO - Journal of Herbal Medicine

JF - Journal of Herbal Medicine

M1 - 100673

ER -

In-vitro antibacterial efficacy of propolis against E. faecalis as compared to other intracanal medicaments: A systematic review and meta-analysis

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