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Immunological axis of curcumin-loaded vesicular drug delivery systems

  • Dinesh K. Chellappan
  • , Zhao Yin Ng
  • , Jin Ying Wong
  • , Alan Hsu
  • , Peter Wark
  • , Nicole Hansbro
  • , Jack Taylor
  • , Jithendra Panneerselvam
  • , Thiagarajan Madheswaran
  • , Gaurav Gupta
  • , Mary Bebawy
  • , Philip M. Hansbro
  • , Kamal Dua
  • International Medical University
  • University of Newcastle
  • University of Technology Sydney
  • Jaipur National University

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

Several vesicular systems loaded with curcumin have found their way in the therapeutic applications of several diseases, primarily acting through their immunological pathways. Such systems use particles at a nanoscale range, bringing about their intended use through a range of complex mechanisms. Apart from delivering drug substances into target tissues, these vesicular systems also effectively overcome problems like insolubility and unequal drug distribution. Several mechanisms are explored lately by different workers, and interest over vesicular curcumin has been renewed in the past decade. This commentary discusses several immunological targets in which curcumin is employed in a vesicular form.

Original languageEnglish
Pages (from-to)839-844
Number of pages6
JournalFuture Medicinal Chemistry
Volume10
Issue number8
DOIs
StatePublished - Apr 2018
Externally publishedYes

Keywords

  • curcumin
  • drug delivery
  • immunological axis
  • liposomes
  • nanoparticles
  • vesicular systems

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