Human gingival crevicular fluids (GCF) proteomics: An overview

Zohaib Khurshid; Maria Mali; Mustafa Naseem; Shariq Najeeb; Muhammad Sohail Zafar

doi:10.3390/dj5010012

Human gingival crevicular fluids (GCF) proteomics: An overview

Zohaib Khurshid
, Maria Mali
, Mustafa Naseem
, Shariq Najeeb
, Muhammad Sohail Zafar

King Faisal University
Fatima Jinnah Dental College
Dar Al Uloom University
Riyadh
Taibah University
Riphah International University

Research output: Contribution to journal › Review article › peer-review

100 Scopus citations

Abstract

Like other fluids of the human body, a gingival crevicular fluid (GCF) contains proteins, a diverse population of cells, desquamated epithelial cells, and bacteria from adjacent plaque. Proteomic tools have revolutionized the characterization of proteins and peptides and the detection of early disease changes in the human body. Gingival crevicular fluids (GCFs) are a very specific oral cavity fluid that represents periodontal health. Due to their non-invasive sampling, they have attracted proteome research and are used as diagnostic fluids for periodontal diseases and drug analysis. The aim of this review is to explore the proteomic science of gingival crevicular fluids (GCFs), their physiology, and their role in disease detection.

Original language	English
Article number	12
Journal	Dentistry Journal
Volume	5
Issue number	1
DOIs	https://doi.org/10.3390/dj5010012
State	Published - Mar 2017
Externally published	Yes

Keywords

Biomarkers
Dentistry
Gingival crevicular fluids (GCFs)
Proteins
Proteomics

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10.3390/dj5010012

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title = "Human gingival crevicular fluids (GCF) proteomics: An overview",

abstract = "Like other fluids of the human body, a gingival crevicular fluid (GCF) contains proteins, a diverse population of cells, desquamated epithelial cells, and bacteria from adjacent plaque. Proteomic tools have revolutionized the characterization of proteins and peptides and the detection of early disease changes in the human body. Gingival crevicular fluids (GCFs) are a very specific oral cavity fluid that represents periodontal health. Due to their non-invasive sampling, they have attracted proteome research and are used as diagnostic fluids for periodontal diseases and drug analysis. The aim of this review is to explore the proteomic science of gingival crevicular fluids (GCFs), their physiology, and their role in disease detection.",

keywords = "Biomarkers, Dentistry, Gingival crevicular fluids (GCFs), Proteins, Proteomics",

author = "Zohaib Khurshid and Maria Mali and Mustafa Naseem and Shariq Najeeb and Zafar, \{Muhammad Sohail\}",

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year = "2017",

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doi = "10.3390/dj5010012",

language = "English",

volume = "5",

journal = "Dentistry Journal",

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T1 - Human gingival crevicular fluids (GCF) proteomics

T2 - An overview

AU - Khurshid, Zohaib

AU - Mali, Maria

AU - Naseem, Mustafa

AU - Najeeb, Shariq

AU - Zafar, Muhammad Sohail

PY - 2017/3

Y1 - 2017/3

N2 - Like other fluids of the human body, a gingival crevicular fluid (GCF) contains proteins, a diverse population of cells, desquamated epithelial cells, and bacteria from adjacent plaque. Proteomic tools have revolutionized the characterization of proteins and peptides and the detection of early disease changes in the human body. Gingival crevicular fluids (GCFs) are a very specific oral cavity fluid that represents periodontal health. Due to their non-invasive sampling, they have attracted proteome research and are used as diagnostic fluids for periodontal diseases and drug analysis. The aim of this review is to explore the proteomic science of gingival crevicular fluids (GCFs), their physiology, and their role in disease detection.

AB - Like other fluids of the human body, a gingival crevicular fluid (GCF) contains proteins, a diverse population of cells, desquamated epithelial cells, and bacteria from adjacent plaque. Proteomic tools have revolutionized the characterization of proteins and peptides and the detection of early disease changes in the human body. Gingival crevicular fluids (GCFs) are a very specific oral cavity fluid that represents periodontal health. Due to their non-invasive sampling, they have attracted proteome research and are used as diagnostic fluids for periodontal diseases and drug analysis. The aim of this review is to explore the proteomic science of gingival crevicular fluids (GCFs), their physiology, and their role in disease detection.

KW - Biomarkers

KW - Dentistry

KW - Gingival crevicular fluids (GCFs)

KW - Proteins

KW - Proteomics

UR - https://www.scopus.com/pages/publications/85027534936

U2 - 10.3390/dj5010012

DO - 10.3390/dj5010012

M3 - Review article

AN - SCOPUS:85027534936

SN - 2304-6767

VL - 5

JO - Dentistry Journal

JF - Dentistry Journal

IS - 1

M1 - 12

ER -

Human gingival crevicular fluids (GCF) proteomics: An overview

Abstract

Keywords

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