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Herbal medicines in neurodegenerative disorders: An evolutionary approach through novel drug delivery system

  • Sunil Kumar Dubey
  • , Gautam Singhvi
  • , Kowthavarapu Venkata Krishna
  • , Tejas Agnihotri
  • , Ranendra Narayan Saha
  • , Gaurav Gupta
  • Birla Institute of Technology and Science Pilani
  • Jaipur National University

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Neurodegenerative disorders are one of the most debilitating, chronic, and often irreversible disorders of the brain and have gained a widespread attention of researchers. Since current therapeutics seem to be inadequate treatment of these disorders, scientists are exploring their options with herbal drugs. This review discusses herbal constituents with the potential to treat neurological disorders. These herbal drugs, when combined with a novel delivery system, provide added advantages to nanocarrier systems. The review also presents research on different herbals through liposomes, polymeric nanoparticles, and solid lipid nanoparticles. The data are collected from various online databases, including PubMed, ScienceDirect, references from relevant review articles, and other official publications. Broad search term criteria are followed for searches so that all pertinent information is included.

Original languageEnglish
Pages (from-to)199-208
Number of pages10
JournalJournal of Environmental Pathology, Toxicology and Oncology
Volume37
Issue number3
DOIs
StatePublished - 2018
Externally publishedYes

Keywords

  • Alzheimer’s disease
  • Herbal drugs
  • Mitochondrial dysfunction
  • Novel delivery system
  • Oxidative stress

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