Green Synthesis of Silver Nanoparticles Using Coriandrum sativum Extract and Their Antioxidant, Anti-inflammatory and Antibacterial Activities Against UTI Pathogens

This study explored the green synthesis of silver nanoparticles (AgNPs) utilizing Coriandrum sativum extract and investigated their potential applications in terms of antibacterial and antioxidant activities. UV‒visible absorption spectra revealed a distinctive absorption peak at 450 nm, indicating successful AgNPs synthesis and stabilization with Coriandrum sativum extract and the TEM analysis revealed the shape to be spherical and size was found to range between 5-25 nm. Antibacterial assays revealed concentration-dependent zones of inhibition against Staphylococcus aureus, Escherichia coli, Pseudomonas sp., and Klebsiella sp., confirming the efficacy of Coriandrum sativum-mediated AgNPs as antibacterial agents. The AgNPs exhibited significant antioxidant properties, with concentration-dependent scavenging activities observed in the DPPH, hydrogen peroxide, and FRAP assays. Protein denaturation assays revealed concentration-dependent effects, suggesting potential applications in biological and medicinal contexts. Additionally, membrane stabilization assays revealed the robust concentration-dependent impact of Coriandrum sativum-mediated AgNPs, underscoring their promising role in diverse applications, from antibacterial treatments to antioxidant therapies and protein stability studies.