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Extinction and positive recurrence of a regime-switching HIV/AIDS model with treatment and standard incidence

  • Qingdao University
  • China University of Petroleum (East China)
  • King Abdulaziz University
  • Quaid-I-Azam University

Research output: Contribution to journalArticlepeer-review

Abstract

In this paper, we investigate the dynamics of a high-dimensional human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) model with treatment and standard incidence, which is perturbed by telegraph noise. The switching is formulated by a continuous time Markov chain. Firstly, we show the existence and uniqueness of the global positive solution. Then, conditions for extinction of the disease are established. Moreover, through constructing suitable Lyapunov functions, we derive sufficient conditions for the existence of positive recurrence of the solutions. Positive recurrence implies all the individuals can coexist and persist in the long term. Finally, numerical experiments are performed for supporting the theoretical results.

Original languageEnglish
Pages (from-to)10982-11002
Number of pages21
JournalMathematical Methods in the Applied Sciences
Volume45
Issue number17
DOIs
StatePublished - 30 Nov 2022
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • HIV/AIDS model
  • extinction
  • positive recurrence
  • standard incidence
  • telegraph noise

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