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Exploring the Connection between Gut Microbiota and Depression

  • Surabhi Shakya
  • , Alka Yadav
  • , Preeti Mishra
  • , Amit Kumar Verma
  • , Kamal Dua
  • Mahatma Jyotiba Phule Rohilkhand University
  • Rohilkhand College of Pharmacy
  • Dr. Bhimrao Ambedkar University
  • University of Technology Sydney

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Because of its substantial impact on several health conditions, including mental health, the complex community of billions of bacteria known as the microbiome of the human gut, which resides in the digestive tract, has garnered much interest. The term "microbiota-gut-brain axis" describes the two-way communication channel that connects the central nervous system with the gut. The disruptions within the microbiota of the gut have been linked to several neuropsychiatric illnesses, including autism, depression, schizophrenia, Parkinson's disorder, and autism spectrum disorders. It is unknown how exactly the intestinal microbiome affects or changes conditions associated with neurological conditions. To find new treatment targets, enhance current treatments, and comprehend the function that the gut-brain-microbiota axis for preventing illness, additional study is needed. This article addresses current research examining the connection between their cause of mental illness and microbial dysbiosis.

Original languageEnglish
Title of host publicationCoresource 4
PublisherNova Science Publishers, Inc.
Pages229-240
Number of pages12
ISBN (Electronic)9798901340134
ISBN (Print)9798895309155
StatePublished - 2026
Externally publishedYes

Keywords

  • depression
  • dysbiosis
  • lactobacillus
  • microbiome
  • neurotransmitters

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