Effect of OREGANO oil mediated effervescent denture cleansing granules against oral pathogens

Aim: To evaluate the antimicrobial activity of oregano oil mediated effervescent denture cleansing granules. Materials and Method: Effervescent granules were prepared using citric acid, tartaric acid and sodium bicarbonate in a ratio of 1: 2: 3 by dry method. The citric acid crystals were powdered first and then mixed with tartaric acid. Oregano Oil was mixed with sodium bicarbonate and incorporated with the acid by geometric dilution. It was then sieved and packed in airtight containers. Different concentrations of the prepared oregano effervescent denture cleansing solution was tested against Streptococcus mutans andEnterococcus faecalis and Candida albicans and the zone of inhibition was measured. Result: The effervescent granules prepared with oregano oil showed good antimicrobial activity against the tested microorganisms such as Streptococcus mutans, Enterococcus faecalis and Candida albicans. Conclusion: The effervescent denture cleansing granules prepared with oregano oil were found to be active against the test organisms especially against E faecalis.Hence it may be used for routine cleansing of denture to protect the denture users from infections such as denture stomatitis.