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Effect of enzymes on extraction of andrographolide from Andrographis paniculata Nees

  • Institute of Chemical Technology

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Andrographis paniculata (Family: Acanthaceae) is used- for its bitter tonic, stomachic, antipyretic and laxative properties in ayurveda. The present study consists of utilizing various enzymes and their combination to facilitate the release of andrographolide from polymeric cell matrix, which in turn will facilitate extraction of andrographolide from Andrographis paniculata. Cellulase and Amylase enabled extraction of 0.37% and 0.34% of andrographolide. Cellulase was found to be most effective in releasing andrographolide as compared to other enzymes and enzyme blend.

Original languageEnglish
Article number13
JournalInternational Journal of Pharma and Bio Sciences
Volume1
Issue number1
StatePublished - Jan 2010
Externally publishedYes

Keywords

  • Andrographis paniculata Nees
  • Andrographolide
  • Enzymes
  • Extraction

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