Determination of racecadotril by spectrophotometric method in bulk drug and its formulation

A. Shirwaikar; S. L. Prabu; C. D. Kumar; K. Rajendran; A. Joseph; A. Shirwaikar

Determination of racecadotril by spectrophotometric method in bulk drug and its formulation

A. Shirwaikar
, S. L. Prabu
, C. D. Kumar
, K. Rajendran
, A. Joseph
, A. Shirwaikar

Manipal Academy of Higher Education

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A new simple, sensitive spectrophotometric method in ultra violet region has been developed for the determination of racecadotril in bulk drug and its pharmaceutical formulation. Racecadotril exhibited maximum absorbance at 231nm with apparent molar absorptivity 5.320 × 10³ in methanol. It obeyed Beer's law in the concentration range of 8 - 40 mcg/mL. Results of the analysis were validated statistically and by recovery studies.

Original language	English
Pages (from-to)	13-15
Number of pages	3
Journal	Indian Drugs
Volume	44
Issue number	1
State	Published - Jan 2007
Externally published	Yes

Keywords

Racecadotril
λmax

Cite this

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title = "Determination of racecadotril by spectrophotometric method in bulk drug and its formulation",

abstract = "A new simple, sensitive spectrophotometric method in ultra violet region has been developed for the determination of racecadotril in bulk drug and its pharmaceutical formulation. Racecadotril exhibited maximum absorbance at 231nm with apparent molar absorptivity 5.320 {\texttimes} 103 in methanol. It obeyed Beer's law in the concentration range of 8 - 40 mcg/mL. Results of the analysis were validated statistically and by recovery studies.",

keywords = "Racecadotril, λmax",

author = "A. Shirwaikar and Prabu, \{S. L.\} and Kumar, \{C. D.\} and K. Rajendran and A. Joseph and A. Shirwaikar",

year = "2007",

month = jan,

language = "English",

volume = "44",

pages = "13--15",

journal = "Indian Drugs",

issn = "0019-462X",

publisher = "Indian Drug Manufacturers' Association",

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T1 - Determination of racecadotril by spectrophotometric method in bulk drug and its formulation

AU - Shirwaikar, A.

AU - Prabu, S. L.

AU - Kumar, C. D.

AU - Rajendran, K.

AU - Joseph, A.

AU - Shirwaikar, A.

PY - 2007/1

Y1 - 2007/1

N2 - A new simple, sensitive spectrophotometric method in ultra violet region has been developed for the determination of racecadotril in bulk drug and its pharmaceutical formulation. Racecadotril exhibited maximum absorbance at 231nm with apparent molar absorptivity 5.320 × 103 in methanol. It obeyed Beer's law in the concentration range of 8 - 40 mcg/mL. Results of the analysis were validated statistically and by recovery studies.

AB - A new simple, sensitive spectrophotometric method in ultra violet region has been developed for the determination of racecadotril in bulk drug and its pharmaceutical formulation. Racecadotril exhibited maximum absorbance at 231nm with apparent molar absorptivity 5.320 × 103 in methanol. It obeyed Beer's law in the concentration range of 8 - 40 mcg/mL. Results of the analysis were validated statistically and by recovery studies.

KW - Racecadotril

KW - λmax

UR - https://www.scopus.com/pages/publications/79251535340

M3 - Article

AN - SCOPUS:79251535340

SN - 0019-462X

VL - 44

SP - 13

EP - 15

JO - Indian Drugs

JF - Indian Drugs

IS - 1

ER -

Determination of racecadotril by spectrophotometric method in bulk drug and its formulation

Abstract

Keywords

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